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To investigate the in vivo properties of two particularly puzzling human lipoproteins, lipoprotein (a) (Lp(a)) and high-density lipoprotein (HDL), we have engineered mice to produce human-like analogues in their plasma. Furthermore the change in electrophoretic behaviour of tRNATyr from the liver of thyroidectomized rats suggests a structural modification of one of the isoacceptors in relation to the change in thyroid status. Using several analogs of quinidine we determined that MCF-7 cell cycle exit and differentiation are typical of quinoline antimalarial drugs bearing a tertiary amine side chain (chloroquine, quinine, quinidine).

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Factors other than income appear to be more important to predict greater prevalence of periodontal disease, but this insight requires further investigation. The onset of bone destruction of the angle and ascending ramus of the mandible as seen on a subsequent x-ray can be placed somewhere in this period of time.

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In addition, PUVA did not cause a significant alteration in the histamine content of the skin. The results indicate that cohorts following large birth cohorts in the cycle choose relatively less formal schooling compared to pre-peak cohorts, and that post-peak cohorts also have lower incomes. Taxes on Sugar-Sweetened Beverages: A Strategy to Reduce Epidemics of Diabetes, Obesity, and Dental Caries?

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Inhibitory effect of oxidized glutathione on heart ornithine decarboxylase activity. It is obvious that prevention, detection, and treatment are all closely intertwined. A comparison of the behavioral effects of proteo-and deutero-N, N-dimethyltryptamine. The prospects for the development of this class of proteins in human therapy are considered. To assess the influence of 14-3-3-beta in modulating the migration and invasion of human glioma cells.

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Solubilization, separation and purification procedures for rabbit pulmonary mixed-function oxidase (MFO) system have been shown to influence the NADPH cytochrome P-450 reductase component activity in the reconstituted system. Surprisingly, we found that cellular sensitivity to Myc-induced apoptosis was retained in tumours from these mice and in most lymphoma cell lines, even when null for p53.

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We treated 6 patients opting for different surgical procedures, depending on the deformity detected. Delipidation of the bacterial cells stimulated the production of a necrotizing focus.

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The possible role of lovastatin in the conservative treatment of this disorder is discussed. However, the relationship between the actual pulmonary capillary wedge pressure and closing volume has not been established. The effects of tetrandrine on activity of collagenase derived from human hypertrophic scar A novel device for hands-free positioning and adjustment of the surgical microscope.

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AM rates decreased to almost one-third, with overall figures remaining fairly low, and affecting to a greater extent highly localized areas and groups of the country. The encoded protein is predicted to contain an N-terminal signal peptide, an extracellular domain with seven imperfect leucine-rich repeats, a single hydrophobic transmembrane segment, and a kinase-like intracellular domain which lacks, however, several of the key conserved residues essential for catalytic activity. Through allele-specific polymerase chain reaction (AS-PCR) amplification and cloning, a total of 13 HMW-GS encoding genes from diploid, tetraploid and hexaploid Brachypodium species were obtained, and all of them had typical structural features of y-type HMW-GS genes from common wheat and related species, particularly more similar to the 1Dy12 gene. Plasma and urinary catecholamines and their metabolites were estimated in 18 patients with borderline hypertension (BH), 27 patients with established hypertension (EH) and 15 healthy subjects in basal conditions and after 20-min standing. gasseri had only mild effects on the transcriptome but modified the gene expression induced by E.

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Macrophages play a crucial role in the pathogenesis of idiopathic pulmonary fibrosis (IPF). Progression of lower urinary tract symptoms after discontinuation of 1 medication from 2-year combined alpha-blocker and 5-alpha-reductase inhibitor therapy for benign prostatic hyperplasia in men--a randomized multicenter study. Method to assess quality of services in antenatal clinics of primary health centres. This steroid response appears to be heritable and alleles in the SFRS3 and FKBP4 genes have recently been suggested to play a role.

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Fully-connected triads (FCTs), such as the Oct4-Sox2-Nanog triad, have been implicated as recurring transcriptional motifs embedded within the regulatory networks that specify and maintain cellular states. Some claim that the resources of the Earth are already overtaxed with ever-worsening environmental pollution. Lethal Pallister-Killian syndrome: phenotypic similarity with Fryns syndrome.

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A number of cautions--some of them very early--make it clear that practitioners were not oblivious to the bureaucratic constraints and political realities Professor Field now identifies. For ATP7A(P1386S) , flow cytometry documented that nonpermeabilized fibroblasts bound a C-terminal ATP7A antibody, suggesting unstable insertion of the eighth transmembrane segment due to a helix-breaker effect of the amino acid substitution.

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In the tricuspid atresia group, there were seven hospital deaths and six late deaths, leaving 28 survivors 11-16 years after surgery. The acceleration by polylysine of the activation of factor X by factor IXa.

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For Bacteria this interaction serves three recognisable physiological functions: provision of energy, protection against excess radiation and signalling (for motility and gene expression). In female lampreys that were injected twice with 50 microg/ml GnRH I or III, 15alpha-T concentrations did not exceed 0.5 ng/ml and 15alpha-P concentrations did not exceed 1 ng/ml.

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This chapter will address communication with patients, families, and health care professionals. Adding the head-tilt-chin-lift technique to adult compression-only CPR by untrained bystanders. The finding that MLT stimulates IL-12 production from human monocytes only if incubated in presence of IL-2 further supports this concept. The labelling of dispensed medicines for the elderly patient: a pilot survey. We tested the hypothesis that a time-dependent myocardial depression caused by EtOH is initiated by its direct and indirect (cardiac vagal dominance) effects and is exacerbated by gradual development of oxidative stress.

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The circulant diallel method using mixed modeling was effective in the classification of genitors regarding their combining abilities relative to the complete diallels. nov., a moderately halophilic, endophytic bacterium isolated from a poplar tree, and emended description of the genus Lentibacillus.

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Immobilized horseradish peroxidase as a reusable catalyst for emulsion polymerization. Characterization and accumulation of ferritin in hepatocyte nuclei of mice with iron overload. However, mice on a k background are highly susceptible to neonatal infection and develop the clinical syndrome of pituitary dwarfism and hypoglycemia. The nursing profession is slowly realising that its role is inter-dependent with that of medicine, Professor George Castle- dine, Head of the Department of Nursing and Community Health at Birmingham Polytechnic, told the conference. Effects of zirconium silicate chewing gum on plaque and gingivitis.

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The field of transforming growth factor-beta (TGF-beta) signaling sees periodic discoveries that revolutionize our thinking, redirect our experiments, and peak our excitement. Our results highlight the potential for negative human health effects related to the consumption of these food products in St. Recently, the selective 5-HT1 receptor agonist sumatriptan has become available and been shown to have significant benefits over traditional therapies for the acute treatment of migraine. mRNA expression was examined using polymerase chain reaction with primers specific for the beta A and beta B chains of activin and by slot blot analysis with a probe specific for the beta A chain. Spectrum of renal osteodystrophy in children on continuous ambulatory peritoneal dialysis.

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The amniotic cells plus collagen I complex was created to mimic the architecture of native amnion. Synthesis and biological evaluation of novel oxindole-based RTK inhibitors as anti-cancer agents. Whilst primiparous cows had generally lower DMI and ECM as compared to multiparous cows, only in primiparous cows a negative effect of lucerne TMR on ECM was observed, especially in early lactation. A relatively large and fairly consistent body of evidence now demonstrates that overweight and obesity in childhood and adolescence have adverse consequences on premature mortality and physical morbidity in adulthood. Here, we develop and validate the quality of a machine reading system, PaleoDeepDive, that automatically locates and extracts data from heterogeneous text, tables, and figures in publications.

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The hSSB1 orthologue Obfc2b is essential for skeletogenesis but dispensable for the DNA damage response in vivo. We document, for the first time to our knowledge, the associations between retinal vessel alterations and subclinical WM pathology among obese adolescents with MetS. Dim down the lights: implementing quiet time in the coronary care unit.

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After a 75-day observation period, blood from the recipient intact sheep was subinoculated into 3 splenectomized sheep. Rapid health needs assessment experience in 11 august 2012 East azerbaijan earthquakes: a qualitative study. Patients admitted to the ED between January 2001 and August 2011 and transfused emergency-release O- RBCs were identified.

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Bone distraction using an external fixator: a new mandibular lengthening technic. Expression of two cell surface polypeptides was positively correlated with retention of specific human chromosomes: a polypeptide of molecular weight 250,000 and isoelectric point 8.3 with the human 5, and a polypeptide of molecular weight 250,000 and isoelectric point 7.0 with the human 2. Two attitude questionnaires (rating scale) were passed to a sample of 36 students of Medicine, randomly elected. By applying philological methods, the authors of different chapters of Lingnan Weisheng Fang (Lingnan Hygiene Prescription) were investigated based on historical materials and epitaphs. Several cytokine pathways have been genetically associated with ankylosing spondylitis (AS), the prototypic subtype of SpA, and additional evidence from human and animal studies support a role of these pathways in the disease.

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While many in vitro investigations have compared the proliferation of periodontal ligament (PDL) cells and gingival fibroblasts (GF), there are no reports directly comparing the abilities of these 2 cell types to fill a wound site. Intra- and interobserver variabilities were assessed using Kappa analysis.

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History of post-ERCP pancreatitis is an independent risk factor for a new episode, suggesting a genetic background. We conclude that the spread of HPAI H5N1 virus from Russia and Kazakhstan to the Black Sea basin is consistent in space and time with the hypothesis that birds in the Anatidae family have seeded the virus along their autumn migration routes. In addition to the director modes, the fluctuation spectrum reveals an additional mode that is attributed to diffusion of structural defects in the column-like aggregates. We illustrate this methodology through a case study data on outbreaks of foot-and-mouth disease (FMD) in Viet Nam for the period 2006-2008. Minimally invasive approaches to the care of thoracolumbar injuries have become more popular, thus, the evidence regarding their efficacy is presented.

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