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The frequencies of oscillatory curves at two symmetrical points of an individual were not different, but a significant difference in the oscillatory cycle was recognized at two asymmetrical points. As a first step to delineating signaling mechanisms governing adverse structural alterations in the hypertensive lungs, we examined changes in the steady-state levels of mRNAs encoding several growth factors including transforming growth factors (TGF), platelet-derived growth factors (PDGF), vascular endothelial cell growth factor (VEGF) and endothelin (ET) as a function of time in MCT-induced pulmonary hypertension in rats. Thirty-four men with sperm density between 5 and 20 x 10(6) sperm/mL, normal serum gonadotropins and T, and a fertile partner were enrolled in this study. In the final experiment, the decrease of renin and angiotensin II/III during superfusion with digoxin 10(-5) mol/l was significantly greater than that observed during superfusion with digoxin in the presence of antidigoxin antibodies. Important aspects of practical implementation are reviewed and reported applications of this methodology are presented.

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Prospective cohort study with risk factors (health behaviours (smoking, alcohol consumption, diet, and physical activity), body mass index, and biological risk markers (systolic blood pressure, triglycerides and high density lipoprotein cholesterol)) measured four times and diabetes status assessed seven times between 1991-93 and 2007-09. The pseudo-first-order constants in aniline concentrations were calculated. Mimicking of mitral stenosis by asymmetrical hypertrophic cardiomyopathy The interstitial pneumonia and the fibrosis and carcinoma are confirmed in all cases. Peripheral antinociception and anti-edematogenic effect of a sulfated polysaccharide from Acanthophora muscoides.

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The anatomy of visuospatial construction revealed by lesion-symptom mapping. Metastasis suppressors in breast cancers: mechanistic insights and clinical potential. They were located in the left atrium in five cases and in the right side in one case. Certain cell fate decisions can have precise requirements for levels of Notch signaling controlled through modulatory regulation. We conclude that activity in the nMLF provides postural control of tail orientation and thus steers the direction of swimming.

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MSTN, mTOR and FoxO4 are involved in the enhancement of breast muscle growth by methionine in broilers with lower hatching weight. Royal College of Nursing (RCN) General Secretary Christine Hancock believes a new agenda is now clearly emerging for the NHS but that nurses are inadequately prepared for the changes ahead. FPCs in the spinal trigeminal nucleus, the parvocellular reticular nucleus, and the nucleus of the solitary tract were more frequent than the sham-operated rats. Stem cells were first observed in the bone marrow at 15-16 wk of gestation, although bone marrow cultures from earlier fetuses showed heavy growths of stromal cells. The research focuses on improving preoperative treatment: new drugs, new schemes of chemo-radiotherapy (usually induction or consolidation schemes) or optimization of radiotherapy and its effects.

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Changes in high density lipoproteins in patients with hepatobiliary diseases. An attempt to apply the William Brass method to estimate the level of fertility of Tunisian women Men belonging to the manual socioeconomic groups also used services and consulted doctors more often than those in the non-manual groups. Analysis of the receptor complement for insulin and insulin-like growth factor I (IGF-I) in the rat visceral yolk sac. Lymphoma occurring in patients over 90 years of age: characteristics, outcomes, and prognostic factors.

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This system is critical for tsetse fecundity and provides a potential target for development of a reproductive inhibitor. The train-of-four ratio was used to divide the suxamethonium neuromuscular block into phase 1 and phase 2 components. It is recommended to use screening procedures for the identification of individuals with HI and to refer them for further audiologic evaluation. In the kidney, reirradiation tolerance actually decreases with time, indicative of further progression of subclinical damage from the first treatment.

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Reducing the morbidity and mortality associated with gastric cancer requires early diagnosis, which can be facilitated by applying gastroscopy more frequently in high-risk groups. Intranasal administration of DA was shown to increase extracellular DA in the striatum, to have antidepressant action and to improve attention and working memory in rats.

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It was found that the normally hearing group had no difficulty localising sounds in contrast to the majority of hearing-impaired children. The purpose of this study was to describe the quality of life of people six months post percutaneous transluminal coronary angioplasty (PTCA).

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Effect of graded infusion rates of propofol on regional and global left ventricular function in the dog. Clinical manifestation and pathological change of autoimmune hepatitis However, at eight weeks of age, prenatally diazepam-treated animals showed a significantly higher LPS-induced TNF-alpha release than control rats. Con A Sepharose beads can be translocated over the surface of the protozoan Gregarina and in (forward) moving gregarines, the bead may be moved backwards relative to the substrate. Population pharmacokinetics of maslinic acid, a triterpene from olives, after intravenous and oral administration in rats.

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Low power open-aperture z-scan measurements (sensitive to absorptive nonlinearities) revealed a stepwise two-photon excitation of the active layer, through an intermediate state. Because of simultaneous correction of numerous other forefoot problems, it was not possible to specifically isolate or evaluate the effects and benefits of this osteotomy using outcomes measures.

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Even though the revascularization pattern was similar in the 2 groups, the meniscus body showed vessel growth mainly at the adhesion margin for less than one-third of the meniscus transverse diameter, and no significant vascular distribution was found at the free margin. This is the first report of a ring-shaped, primary cyst of the iris pigment epithelium.

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Impacts of urbanisation level and distance from potential natural mosquito breeding habitats on the abundance of canine dirofilariosis. This lithotomy technique is a safe and reliable nonsurgical technique for patients with cholecystolithiasis, especially the elderly high-risk group. Completeness of TNM cancer staging for melanoma in the Danish Cancer Registry, 2004-2009. The theoretical and computational methods presented here provide the basic tools to model high resolution Raman images at the single molecular level. The other alpha1-adrenoceptor subtypes could also mediate the secondary contractile response to noradrenaline in this artery.

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The data supports the idea that dexamethasone induced changes in the distribution of tumor water were mediated by changes in capillary permeability and tumor blood flow. Based on this finding we suggest that some antibodies elicited by influenza vaccines act as agonists, which activate a BKB2R-associated signaling pathway contributing to the protection against CVD. Recent evidence suggests that fibrocystin/polyductin (FPC), polycystin-1 (PC1), and polycystin-2 (PC2) are all localized at the plasma membrane and the primary cilium, where PC1 and PC2 contribute to fluid flow sensation and may function in the same mechanotransduction pathways. We investigated the effects of vitamin D deficiency on long-term outcomes of patients with chronic hepatitis B (CHB). These effects could consequently affect the accuracy of analytical results, so that they need to be considered for the analysis of real samples.

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Alteration of intracellular calcium distribution in the adipose tissue of patients with essential hypertension. Prostatectomized patients had worse scores on the QoL scale, with exception of the urinary disturbance dimension. The formation of ice crystals in the laboratory and the atmosphere.

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In the experiments carried out on Wistar rats it was demonstrated that pilocarpine was without effect on the GABA level in the cerebral cortex, while physostigmine raised this level. Severe aortic and mitral regurgitation, severe biventricular impairment and pulmonary hypertension were confirmed on transthoracic and transoesophageal echocardiography. Effect of insulin on the proline transport activity in cultured fibroblasts from patients with Werner syndrome. CCCDs race, educational status and attitudes towards oral health strongly predicted their intention to implement OHPPs. After the onset of labor, prekallikrein decreases rapidly which may trigger changes in the blood coagulation and fibrinolytic system.

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Simultaneously successful transfemoral aortic valve implantation and endovascular repair of thoracic aortic saccular aneurysm. High temperature combined with drought affect rainfed spring wheat and barley in South-Eastern Russia: I. A series of gold(I) triphenylphosphine (PPh3) complexes (1-9) involving 2-chloro-N6-(substituted-benzyl)adenine derivatives as N-donor ligands was synthesized and thoroughly characterized by relevant methods, including electrospray-ionization (ESI) mass spectrometry and multinuclear NMR spectroscopy.

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Transmembrane segment S4 of voltage-gated sodium channels resides in a gating pore where it senses the membrane potential and controls channel gating. Inclusion of objective vestibular tests in the concussion protocol may reveal the presence of peripheral vestibular or visual-vestibular deficits.

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Therefore, copper is not considered to be an important factor in diabetes mellitus. Preliminary studies on the transformation of nitrosugars into branched chain iminosugars: synthesis of 1,4-dideoxy-4-C-hydroxymethyl-1,4-imino-pentanols. Evidence for binding and activation properties of saposins C with acid beta-glucosidase. Clinical consequences of drugs interactions vary in severity from mild to lethal events. Inhibition and resumption of replicon initiation in X-irradiated mouse L5178Y cells.

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Immunological and virological markers determining progression to AIDS. Aneurysmal rupture in this model can be easily detected by assessing neurological symptoms. Report on a gerontological lecture tour in the Peoples Republic of China

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Despite their importance, lack of Net or fra affects only some commissures, suggesting that additional molecules can fulfill this function. Effect of human chorionic gonadotropin on plasma concentrations of 17-hydroxycorticosteroids, dehydroepiandrosterone and androsterone in man. Tinnitus aurium: observations on the effect of curare on loudness level. Vascularization, blood circulation, histological characteristics of the grafted meniscus and surrounding tissues, and vascular endothelial growth factor (VEGF) expression in the meniscus were assessed at 4, 8, and 12 weeks after allograft or autologous transplantation.

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Complement C5A antagonist treatment improves the acute circulatory and inflammatory consequences of experimental cardiac tamponade. In this paper I focus on delusions that have been construed as playing a defensive function (motivated delusions) and argue that some of their psychological benefits can convert into epistemic ones. Ordination by multi-dimensional scaling indicated that the species were separable, and that hybrids resembled L.

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Cultured preadipocytes derived from the stromal-vascular fraction of adipose tissue have been shown to accumulate sufficient triglycerides to assume adipocyte morphology when exposed to high concentrations of very low density lipoprotein. However, there has been no evaluation study for the accuracy and usefulness of these services. Several recent policies seem to be taking the NHS away from the goal of an equitable system--for example, the new arrangements for community care and the incentives within contracting to select patients on financial grounds.

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Auditory brainstem responses were obtained from 52 alcoholic patients with or without neurological complications of alcoholism. Neural correlates of language and non-language visuospatial processing in adolescents with reading disability. Effect of cooling rates and temperatures on quality and safety of quahog clams (Mercenaria mercenaria). The enhanced contractile response to BaCl2 could not be related to the presence or severity of symptoms or to any other of the variables mentioned above. In addition, GnRH synthesized by the mammary gland may also affect the mother by a paracrine and/or an endocrine mechanism.

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Dendritic architectures of neurons in the medial prefrontal cortex (mPFC) and basolateral amygdala (BLA) were examined. Among the adverse effects due to corticosteroids, bone loss and cardiovascular risk should be carefully monitored. The use of the adaptive optics (AO) enables the measurement and manipulation of conventional lower order aberrations (defocus, astigmatism) and for HOAs as well. NoiseScan also predicts the development of hearing loss in individuals in 5-year periods. Sleep period was considered as one of no less than 2 hours, nocturnal BP fall was defined as the difference between awake and sleep means, and dipper condition as a systolic decrease greater than 10 mmHg and diastolic decrease greater than 5 mmHg.

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The placing reaction in the standing cat permits the analysis of a movement, the placing movement, together with its postural support. With an ageing population there is an increasing number of patients with severe multilevel atherosclerosis. The results from the biochemical and spectroscopic characterization showed that the photosystem II antenna is loosely bound to the reaction center, whereas the association is stronger in photosystem I, with the antenna-reaction center super-complexes surviving purification.

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We tested the effects of TGF-beta 1 and the cAMP-inducing agent, forskolin, on the viability of resting B cells from human peripheral blood, and found that both agents caused a significant, dose-dependent increase in cell death relative to spontaneous death in medium alone, as measured by vital dye staining with propidium iodide. lineatum, produced a distinct dermal reaction in cattle infected with the first-instar larvae of either species, but not in cattle in which the infection could not be confirmed later either on necropsy or by the appearance of warbles in the back.

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A multivariate analysis of infant mortality in developing countries. G protein-coupled receptors form stable complexes with inwardly rectifying potassium channels and adenylyl cyclase. However, these polymorphisms are merely correlative, and other molecular determinants of susceptibility have remained largely unknown.

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Experiments were designed to explore the influence of wind speed and steepness of climb on accuracy of Pest. Genetic heterogeneity and clinical variability in the Sanfilippo syndrome (types A, B, and C).

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Cross resistance was higher between Cry4Ba and Cry11Aa than between Cry4Aa and either Cry4Ba or Cry11Aa, suggesting both common and specific mechanisms of resistance. Covalent binding, on the other hand, orientates all immobilized compounds in a defined way on the solid phase, thereby exposing the interacting sites on the enzymes, antibodies, gene probes, etc.

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In vitro experiments were done for investigating the interactions of the three 3H-labelled alkylating drugs cyclophosphamide, ifosfamide and trofosfamide with DNA and DNA-constituents. This may suggest that the melanosomes are not produced in the Merkel cell, but are taken from the melanocytes like in keratinocytes. The CosSHa.tet vector was created from a large PrP cosmid clone in which the PrP open reading frame was deleted. All sera positive for anti-HBs and negative for anti-HBc and most sera positive for anti-HBc but negative for anti-HBs were anti-HBe-negative.

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miR-143 decreases COX-2 mRNA stability and expression in pancreatic cancer cells. Effect of steroid hormones on serotonin, norepinephrine and epinephrine contents in the pineal-paraphyseal complex of the soft-shelled turtle (Lissemys punctata punctata). Human adenovirus-36 (Adv36) increases adiposity, but also upregulates distal insulin signaling in vitro in human adipose and muscle tissue and in vivo in the rodent independently of adiposity.

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This recovery stroke is coupled to the activation of myosin ATPase by a mechanism that is essential for an efficient motor cycle. We show that thrombin increased neuronal excitability in the immature hippocampus in an N-methyl-D-aspartate-independent manner.