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Clinical data of 1366 colorectal cancer patients undergoing radical resection by the same surgical team in our hospital from January 2000 to September 2011 were analyzed retrospectively. All five cases were observed among the 14 patients who had received four or more doses of the drug. Overlap syndrome consisting of PSC-AIH with concomitant presence of a membranous glomerulonephritis and ulcerative colitis.

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Syn-aldehydes, syn-4a and syn-4b, both react poorly, affording all four possible diastereoisomeric oxasilacycle products. Thus for certain well-defined indications, echo-endoscopy is now the highest performing imaging technique currently available for lesions of the digestive tract. Comparative effects of prenatal gamma radiation and x-irradiation on the reproductive system of the rat. The elevated cyclic AMP leads to the activation of protein kinases which are essential in phosphorylating the lysosomal hydrolases released by hypoxia into the cytosol of the cell and may be the precursors of erythropoietin. Preliminary study of kidney and threshold of hearing in middle aged people of Tu tribe in Qinghai Province

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Cost control and accountability are requirements in the academic world of the 1990s. It is likely that monosodium glutamate (MSG) is the excitotoxin that has been most commonly employed to characterize the process of excitotoxicity and to improve understanding of the ways that this process is related to several pathological conditions of the central nervous system. The biodistributions and in vivo kinetics of chemically prepared neoglycoproteins have been examined previously and are reviewed here. Urokinase plasminogen activator system in synovial fibroblasts from osteoarthritis patients: modulation by inflammatory mediators and neuropeptides.

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The difference in HRV tests among males and females disappears after menopause. Relationships between ten-year trends of tropospheric ozone and temperature over Taiwan. Familial euthyroid hyperthyroxinemia resulting from increased thyroxine binding to thyroxine-binding prealbumin.

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By controlling the regioselectivity of addition into our electrophilic intermediate, we also characterized by which mechanism the Doebner-Miller cyclization step occurred. Alteration in expression of MMP-1 and MMP-2 but not TIMP-1 and TIMP-2 in hereditary gingival fibromatosis is mediated by TGF-beta 1 autocrine stimulation. The effects of triamcinolone acetonide on plasma glucocorticoid levels and occurrence of estrus in gilts. Nine cases of giant unclippable aneurysms treated with the detachable balloon technique are reported.

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Giant polytene chromosomes from the ovaries of a Drosophila mutant. It is associated with increased brush-border NHE3 and association between ezrin and NHE3. A retrospective chart review was performed on consecutive pseudophakic adult patients with uncontrolled glaucoma undergoing AGV with and without intraoperative subtenon TA injection by a single surgeon.

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A re-examination of the rationale for auto- or homo-grafting of cutaneous injuries and a preliminary report on the action of plastic dressings. In postpartum females (relative to virgins), tissue levels of glutamate and GABA were elevated in LS and increased mRNA was found for the respective enzymes producing glutamate and GABA, glutaminase (Gls) and glutamate decarboxylase 1 and 2 (Gad1 and Gad2). Because polyenylphosphatidylcholine (PPC), a soybean extract rich in polyunsaturated phosphatidylcholines, decreases the induction of ethanol-specific CYP2E1 and opposes oxidative stress, we hypothesized that PPC supplementation may attenuate hepatocyte apoptosis caused by ethanol ingestion.

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Conversely, DGKalpha-knockdown considerably inhibited the NF-kappaB activity. The purpose of this review is to assess the clinical impact of recent advances in the epidemiology, prevention, and management of CHD in diabetic patients. The overall rate of severe hypoglycemia remains largely unchanged. An acceleration of age-related increases in levels of the beta-subunit of nerve growth factor in selected tissues from senescence-accelerated mice (SAM-P/8). An analysis of certain chemical constituents of rabbit bone following deposition of 90Sr.

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In patients with spinal cord infarction, the MEP study can demonstrate spinal involvement even when radiological evidence for spinal cord damage is absent or equivocal, thus allowing an important early diagnosis. Structure prediction and functional analysis of a non-permutated lectin from Dioclea grandiflora.

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Event-by-event respiratory motion correction for PET with 3D internal-1D external motion correlation. The products of these enzymes, 1,25-dihydroxycholecalciferol and 24,25-dihydroxycholecalciferol, were extracted from the in vitro incubation mixtures, isolated and purified by gel filtration and high-performance liquid chromatography, identified by ultraviolet absorption spectrometry, and high performance liquid chromatography with a second solvent system and quantified relative to authentic standards with a 254-nm detector system. Perspectives in scientific communication: past, present, and future directions. Although this disease is considered to be self-limiting in the majority of cases, surgical intervention can be considered in unusually large cases. A novel amphoteric copolymer flocculant was synthesized by incorporating a cationic moiety 2,3-epoxypropyl trimethyl ammonium chloride (GTA) and an anion moiety phosphate onto the backbone of starch with microwave radiation.

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Association of EPAS1 gene rs4953354 polymorphism with susceptibility to lung adenocarcinoma in female Japanese non-smokers. No simple clinical technique with which to measure the volume of bone gaps in the treatment of open fractures or nonunions of the tibia is currently available. The influence of different maize-soya rations of varying amino acid composition and at several levels of intake on the utilization and endogenous losses of protein in piglets. lysosomes isolated after injection of Triton WR-1339 into the animal. Multiple lncRNAs participate in normal and may be implicated in malignant hematopoiesis associated with blood cell cancers, such as leukemia, by regulating gene expression through such mechanisms as redirecting chromatin remodeling complexes and activating epigenetic silencing, either of which can inactivate tumor suppressor genes or activate oncogenes.

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Induction of micronuclei in mouse bone marrow by the insecticide gardona. These values and the dimensions obtained from electron microscopy suggest that the desmin protofilament contains three or four protein subunits.

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Unfortunately, these techniques are not completely specific for singlet oxygen. We found a high mortality rate in our study population, but the causality of death and chronic periprosthetic hip joint infection cannot be established in this study and this needs further attention. Early specialization of collencytes secures, already at the larval stage, synthesis of a specific protein--collagen. Additionally, the spinal trigeminal nucleus contributes fibers of lingual nerve origin to the contralateral medial lemniscus. We reveal that the growth of higher-order sidebands is strongly influenced by the competition with cascade FWM between the pump and the first-order quasi-phase matched sidebands.

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Furthermore, the increased expression of ethanol stimulant effects in these mice was maintained even after a second procedure of ethanol sensitization. Similar to the use of cortical simulation in the resection of supratentorial gliomas, this technique can potentially advance the safety of intramedullary spinal cord tumor resection. The effect of magnesium sulfate on fetal heart rate (FHR) variability and uterine activity is evaluated in 19 preeclamptic patients at term in active labor.

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For a lesion to be keloidal, the collagen must have a thick hyaline character, sharp edges, and a sparsity of intervening cells and vessels. In 7 cases of CH tested serially during their clinical course, anti-LP-1 and/or anti-THGP tended to appear during acute exacerbations.

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A new generation of non-steroidal anti-inflammatory drugs has been described that selectively targets the inducible isoform of cyclo-oxygenase, cyclo-oxygenase 2 (COX-2). T/T and G/T ratios correctly predicted proximal disease in nine of 12 limbs, while C/C, T/C, T/K ratios correctly predicted distal disease in 21 of 21 involved limbs. Sexual differentiation of male and female job applicants on the draw-a-person test.

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Of 67 players with acute hamstring injuries, 51 underwent ultrasonographic examination of the injured thigh and were included in this study. This is the only method that allows reproducible and valid scaling up from the analytical to the preparative scale. The corresponding aqueous surface NO concentration was 0.09 nM at 250 s(-1) as predicted by a validated model. The parametric differences in ejaculate quality in summer and winter seasons were statistically significant, however, their variations did not exceed the spermiologic standard throughout the year.

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There were no significant differences in mobility between groups. In particular, ceramide has attracted considerable attention in cell biology and biophysics due to its key role in the modulation of membrane physical properties, signaling and cell death regulation. Trans-cultural validation in Italian language showed the validity and reliability of the I-BrQ. The recruitment order of stapedius motoneurons in the acoustic reflex varies with sound laterality.

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During the perioperative period, several factors can trigger coronary vasospasm, including the discontinuation of vasodilators. The multistage sampling techniques were used for selecting 1008 adolescents aged 14-19 years old. Heterozygous SOX2 mutations have recently been reported to cause isolated hypogonadotropic hypogonadism (HH), in addition to ocular and brain abnormalities. Excellent results are obtained in terms of optimality, convergence, and algorithmic efficiency. The aim of the study is to investigate the effects of metalloproteinase-8 (MMP-8) on SIMI and its mechanisms in rats.

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Understanding the cause of effluent toxicity is an important requirement for its prevention, remediation and return to compliance. Patients with hereditary angioedema were investigated for plasma metallopeptidase activities responsible for kinin catabolism (APP, angiotensin I-converting enzyme, and carboxypeptidase N) and for CI-INH function in treated and untreated patients. We were able to verify correlations between the measures themselves, apart from physical health. We postulate that the proteolytic processing and two-subunit structure is a common characteristic feature in the family of GPS-containing adhesion GPCRs. Since the end of the 1980s, African demography has moved in a social and explicative direction.

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A mixed-model health maintenance organization serving approximately 110,000 enrollees in central Colorado. Amplification of the following genes was found: c-myc (2 of 50), hst (3 of 50), c-erbB2 (3 of 50), and c-Ki-ras (5 of 50). Furthermore, the appropriate intensity of physical exercise is critical for post-stroke rehabilitation. In this review, we have reported several popular methods including co-precipitation, microemulsion, thermal decomposition, solvothermal, sonochemical, microwave-assisted, chemical vapor deposition, combustion, carbon arc, and laser pyrolysis, for the synthesis of magnetic nanoparticles.

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Routine pre-transplant MII-pH may provide clinically relevant data regarding transplant outcomes and peri-transplant care. No evidence of obstructive apnoea was found and no apnoea of greater than 12 s duration was observed. Principal-components analysis (PCA) was applied to the items of each instrument. Phonological disorders III: a procedure for assessing severity of involvement.

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STR systems located on the Y chromosome are widely used in forensic science for the identification of male individuals. Liver biopsy, obtained from three of the patients between 5 and 15 months prior to HDV superinfection, showed chronic persistent hepatitis in two and chronic active hepatitis in one. In this review, the available data on the natural habitats of different wood-degrading organisms (with emphasis on the amount of water present during wood degradation) and occurrence of cellulose-binding domains in their genome have been assessed in order to identify evolutionary advantages for the development of CBM-less cellulases in nature. 31p-NMR investigations of phase separation in phosphatidylcholine/phosphatidylethanolamine mixtures. The postoperative course can be complicated by CMV reactivation, which may masquerade either as graft rejection or graft failure.

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These findings show that synovitis was one important predictive factor of pain. Carbonic anhydrase activity of dinuclear Cu(II) complexes with patellamide model ligands. Studies using Human umbilical vein endothelial cells (HUVECs) clearly demonstrated that administration of DAS significantly retarded endothelial cell proliferation, migration, invasion and tube formation.

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We use the analytical expression of these probabilities to derive a novel algorithm which, while ignoring the exact position of the molecules, can still accurately capture diffusion effects. The transcription factor Mlc promotes Vibrio cholerae biofilm formation through repression of phosphotransferase system components. G4-5 and G5-6 each bind a single calcium ion, but there is no binding by G4 or G5. Brain density and cerebrospinal fluid space size: CT of normal volunteers. A prospective study was carried out on 158 anovulatory women for the purpose of finding parameters that might predict the clomiphene dose at which ovulation would occur.

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Cholecystokinin is partly responsible for reduced food intake and body weight loss after total gastrectomy in rats. Invasive aspergillosis should be considered as a cause of refractory pneumonia and of new focal neurologic deficits in patients with hepatic failure.

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The time to maximum isotope activity in each kidney, T(max), was compared with T(max) in 10 control patients, who did not receive diclofenac but underwent two identical renographies. Our findings indicate that poor mental health and specific mental health conditions remain prevalent in primary care. We report changes that occur in cell shape, surface morphology, intercellular junctions, nuclear shape and location, and cytoplasmic organization of supporting cells after trauma. Caused by several species of Clostridia, it is an acute, highly invasive necrotizing infection of muscle and fascia often leading to coma and death. Positive modulation of these forms by both agents markedly declines with the age of the animals.

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Five randomized controlled trials have been published on intrapartum fetal heart rate monitoring with ST analysis of the fetal electrocardiogram, but the debate on its usefulness has not yet been ended. These results indicate that, in addition to its known properties as a local aesthetic, cocaine when applied intranasally exerts an analgesic effect. A total of 139 early young schizophrenia and mood-disordered patients were assessed at index hospitalization and then reassessed six times over 20 years for psychosis and other major variables.

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Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is a proinflammatory cytokine that is involved in pathogenesis of abnormal or disregulated inflammation. The results of this study suggest that physicians should spend more time with dilated glaucoma patients while explaining medical conditions and treatment instructions in order to ensure that patients have adequate time to comprehend instructions for glaucoma management. The renin-angiotensin system (RAS) has pivotal roles in the regulation of normal physiology and the pathogenesis of cardiovascular disease.

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In addition, infected co-evolved finches that lost the most mass harboured the least amounts of MG, whereas the reverse was true in finches from unexposed populations. It is essential to clearly identify clinical phenotypes to achieve optimal treatment of elderly patients with asthma. Work-related health inequalities are determined to some extent by an unequal exposure to chemical and biological risk factors of disease.

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To date, allogeneic stem cell transplant remains the only curative treatment option for patients with relapsed, refractory CLL. Both myelinated and unmyelinated fibers seem to be decreased with the duration of sensory disturbance. These results, together with pulsed field gel electrophoresis data place the boundary between alphoid and satellite III sequences in the mapping interval 10 centromere-10q11.2. The carotid aneurysm is an exception, since the aneurysm will be first, followed by the haematoma. Inotropic responses of isolated atrial and ventricular muscle from the dog heart to inosine, guanosine and adenosine.

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Here, a new approach to make the biodegradable scaffolds entirely radiopaque is explored. In this review we present the most recent data regarding bacterial collagenases and overview the functional and structural diversity of bacterial collagenases. We expect this work to provide useful insights to guide the development of a feasible strategy to overcome the limitations of current technology for electrochemical CO2 conversion. 11 beta-Hydroxysteroid dehydrogenase in the rat placenta: developmental changes and the effects of altered glucocorticoid exposure. Changes in the spatial distribution of the population of the Ukraine between 1959 and 1984 are analyzed.