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Changes in prevalence of prescription opioid abuse after introduction of an abuse-deterrent opioid formulation. These complexes contain a long chain aliphatic diamine where the carbon length is variable and present a hydroxyl group in two different positions. An experience of rapid acceleration in demand for Pap smears in an underserved Latino community of East Los Angeles following the showing of one of these videos is chronicled as a spontaneous and informal evaluation of this approach to health education/promotion video production.

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Short- and midterm outcomes of laparoscopic surgery compared for 131 patients with rectal and rectosigmoid cancer. Calcification of IOL showed deposits which were located in the superficial substance of lens.

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The level of stable translocations in one case (woman, 59 years old) determined using FISH (16.62 per 100 cells for the whole genome) exceeded their spontaneous aged frequency and confirmed the high sensitivity of this method for the evaluation of real radiation exposure. The morphometric pulmonary diffusing capacity per unit body weight (DLO2/W) was 0.02 ml O2 per min per mm Hg per g. Loss of Achilles tendon combined with overlying soft tissue loss is a challenging problem.

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The method, based on a scoring scale, offers simple and easy visualization and identification of resilient, productive and/or contrasting genotypes according to grain yield. In patients with delirious hypochondriac disorders, symptoms of rough deficiency are usually absent. Cross-pinning with smooth K-wires results in a low rate of physeal injury. Phylogenetic relationships in the subobscura cluster based on homologies of chromosome A.

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Those with measurable organic dysfunction or known organic factors were excluded. Mutations of genes common to several tissues or organs can lead to cellular damage, which may result in hearing impairment as part of a syndromic disorder. The aim of this study was to investigate the influence of the amino acid residues at position 7 of GnRH analogues on peptide self-assembly. Maintenance of respiratory rhythm-generation by vascular perfusion with physiological saline in the isolated head of the carp. cerevisiae cells lacking the TSC3 gene have a temperature-sensitive lethal phenotype that is reversed by supplying 3-ketosphinganine, dihydrosphingosine, or phytosphingosine in the growth medium.

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Evaluation of spatial distribution and accumulation of novel brominated flame retardants, HBCD and PBDEs in an Italian subalpine lake using zebra mussel (Dreissena polymorpha). These results could show the spatio-temporal pattern in that information of the stimulus encoding could be processed in cortex.

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Among the peracylated beta-CyDs tested, perbutanoyl-beta-CyD maintained sufficient plasma drug levels for a long period of time, while other peracylated beta-CyDs having shorter or longer chains were inappropriate to control the in-vivo release behaviour of molsidomine. Meta analysis on the association of CYP11B2 gene polymorphism and essential hypertension in Chinese Han population The sensitizing effect of apomorphine was completely prevented in prepubertal rats by pretreatment with EB for 6 days.

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Late arrhythmias in children after surgery of the secundum type of atrial septal defects During hyperaesthesia sensations could be evoked by laser intensities which were below intensities that could be perceived in the awake state.

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Details are given of the injuries sustained by 16 occupants of a coach that overturned. We have used differential hybridization to isolate and characterize two novel cDNAs expressed in chondrocytes and some osteoblastic cells. Response to implementation of rapid cortisol during adrenal vein sampling. Chlorate treatment also reduced the binding of bFGF to growth plate chondrocytes and this effect could be reversed in a dose-dependent manner by the simultaneous addition of sodium sulfate. A simple instrument for endoscopic laryngeal and pharyngeal surgery.

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After controlling for clinically insignificant antibodies, our auto- and alloimmunization rate was much less than previously reported values. Seedlings were transplanted at three different times in late summer and in autumn covering the period of seed germination in the study population.

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The statistical analysis of insect counts based on the negative binomial distribution. Analysis of urinary human growth hormone (hGH) using hydrogel nanoparticles and isoform differential immunoassays after short recombinant hGH treatment: preliminary results. An account is given of stillborn male twins born to a female Saanen goat (Capra hircus) and a Barbary ram (Ammotragus lervia).

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Smoking-related self-efficacy, beliefs, and intention: assessing factorial validity and structural relationships in 9th-12th grade current smokers. Pilot study to evaluate feasibility of image-guided breast-conserving therapy in the advanced multimodal image-guided operating (AMIGO) suite. Optimal paths in complex networks with correlated weights: the worldwide airport network.

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It is concluded that intestinal fatty acids can enhanced acid-induced canine pancreatic secretion. All patients undergoing infrarenal EVAR performed between 2006 and 2009 at our institution were included in the current study. A new ionic liquid matrix (ILM), a guanidinium salt of alpha-cyano-4-hydroxycinnamic acid, facilitates direct UV-MALDI mass spectrometric (MS) analysis of underivatized DS and CS oligosaccharides up to a decasaccharide in their common form as sodium salts. Asparagine synthetase (ASNS) is deemed to be a promising therapeutic target for the treatment of several cancers, but its functional role in human breast cancer is still unknown. Comprehensive control of human papillomavirus infections and related diseases.

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A multiloculated renal mass with thick septum discovered in an adult by ultrasonography or CT scan should be suspected as being a MLCRCC rather than a MLCN. Because the intact distal part of the iliotibial tract is responsible for the pivot shift-sign, a detailed description of its anatomy and physiology is given. This study shows the combined microsurgical epididymal sperm aspiration-intracytoplasmic sperm injection procedure to be highly efficient in achieving fertilization in vitro, even after recovery of grossly impaired epididymal sperm. High blood pressure is a major risk factor for cardiovascular disease. On the other hand, 3-mercaptopropionic acid (10-90 mg kg-1, i.p.), an inhibitor of the GABA synthetizing enzyme glutamic acid decarboxylase, promoted the release of vasopressin when the rats were killed prior to the onset of convulsions.

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We found that both sequence and structural features are important in nucleosome occupancy prediction. A decrease in PRL response is known to occur if there is progression to status epilepticus. The viral enzyme, HIV integrase, is involved in the integration of viral DNA into host cell DNA.

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bCPAP was well accepted by caregivers and patients and can be feasibly implemented into a tertiary African hospital with high-risk patients and limited resources. Ischemic stroke is the most common reported cerebrovascular complication.

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Bioenergy from forestry and changes in atmospheric CO2: reconciling single stand and landscape level approaches. The lung cDNA hybridized to a similarly polydisperse message in ulcerative colitis colon RNA, but did not hybridize to control RNA from U937 lymphoma cells or stomach RNA. Hearing preservation and improvement of auditory brainstem response findings after acoustic neuroma surgery. Herein, we report a polymer/paper hybrid microfluidic biochip integrated with loop-mediated isothermal amplification (LAMP) for multiplexed instrument-free diagnosis of these three major types of bacterial meningitis, with high sensitivity and specificity.

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Plasma lipids, apolipoproteins, and gamma-glutamyl-transpeptidase (GGT) were measured in 28 patients receiving aminoglutethimide (500 mg) and hydrocortisone (30 or 40 mg) for advanced breast cancer. The state of the art in preventing equipment-related Alpine ski injuries. In contrast to C5a in plasma, the concentration of cell-associated C5a correlated with number of PBL or polymorphonuclear leucocytes (PMN). The method of localization has been by the use of a specific cytochemical technique, utilizing a chromium (Cr) complex with an isoquiniline derivative formed by the reaction of the unsubstituted biogenic amine with glutaraldehyde. In this manuscript, we review the complex evaluation needed for defining CD remission versus persistent disease after surgery, and focus on challenges in diagnosing early recurrent hypercortisolemia.

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This study explored the utility of the health belief model (HBM) in explaining medication adherence in subjects with severe and disabling mental disorders. Blood flow recovery was significantly improved in RNF213 -/- from 3 to 28 days after femoral artery ligation, and angiogenesis as shown by vascular density in the hind-limb was significantly enhanced in RNF213 -/- at 28 days. Driving this array by an external oscillatory signal produces a nonzero mean field that follows the driving signal even when the oscillators are not locked to the external signal. T wave changes and postinfarction angina pectoris predictive of recurrent myocardial infarction. Within genetically identical inbred and F1 hybrid test animal populations there exist subpopulations with different levels of sensitivity to induction of toxic endpoints, e.g., neoplasms, in response to toxicant exposure.

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Because of its function as a major juncture linking various insults and injuries associated with inflammatory attack on neuronal cell bodies and axons, it provides potential for the development of neuroprotective strategies. Several similar cases reported in the literature suggests an increased risk of bladder cancer in patients treated with cyclophosphamide. These lesions may be confused radiologically for gastric ulcers or cancers. However, the prognosis is still related to the severity of the anomaly.

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Societal attitudes about the dental care system have not received much attention. Dietary effects on exercising muscle metabolism and performance by 31P-MRS. Dye content was determined by a visual method and subvisually by an ion exchange resin method. Final energies for the reaction barriers were obtained using both MP2 with the aug-cc-pVTZ basis set and coupled cluster theory (CCSD(T)) with the aug-cc-pVDZ basis set.

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In drug discovery laboratories, metabonomics aids in target identification, phenotyping, and the understanding of the biochemical basis of disease and toxicity. Neoaortic bicuspid valve in arterial switch operation: mid-term follow-up.

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Effects of cimetidine on the pharmacokinetics of proguanil in healthy subjects and in peptic ulcer patients. Tracking the dynamics of the social brain: ERP approaches for social cognitive and affective neuroscience.

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Influence of the applied sets of lining and filling materials on the sealing effect of the dental restorations. Systematic investigation of the mechanical properties of pure silica zeolites: stiffness, anisotropy, and negative linear compressibility.

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HBO had a more pronounced effect on these key markers of osteoblast differentiation than elevated oxygen or pressure alone. To analyse whether Adverse Childhood Experiences (ACE) are associated with an increased risk of cancer.

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Angelman syndrome usually has been considered to be rare and sporadic. We analyzed two genes that were sites of frequent transposon insertion and highly expressed in human medulloblastomas: Arnt (aryl hydrocarbon receptor nuclear translocator) and Gdi2 (GDP dissociation inhibitor 2). Follow up of affected workers by questionnaire, spirometry, and assessment of bronchial responsiveness 18 to 24 months after exposure ended. To insert the HSV1-TK gene at the OCT4 locus, we cotransfected hiPSC with a pair of plasmids encoding an OCT4-specific zinc finger nuclease (ZFN) and a donor plasmid harboring a promoter-less transgene cassette consisting of HSV1-TK and puromycin resistance gene sequences, flanked by OCT4 gene sequences. The results show that the frequencies of II-III translocations in the MR-containing males is not significantly higher than in the controls.

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We present a case of laparoscopic transumbilical single incision appendectomy. Before injection into F1 recipients, spleen cells of immunized animals were incubated for 1 h at 37 degrees C in heat-inactivated serum of primiparous pregnant or virgin non-pregnant mice. Runt pigs 12 h after birth had lower proportions of type I fibers in the deep semitendinosus than did normal size pigs, which indicates that in utero stunting delayed the normal differentiation of myofiber histochemical characteristics. The authors provide information on selected sources of demographic data for Venezuela for two historical periods: the pre-statistical years from the beginning of Spanish colonization to the early 1870s and the period from 1870 to the present.

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The present retrospective analysis was performed to evaluate the long-term results of initial periodontal and fixed prosthodontic treatment in patients with gingivitis or moderate chronic periodontitis during post-therapeutic irregular maintenance of 5-17 years. Inhibition of noradrenaline release from the sympathetic nerves of the human saphenous vein via presynaptic 5-HT receptors similar to the 5-HT 1D subtype.

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Prognostic significance of second-degree atrioventricular block in inferior wall acute myocardial infarction. This correlation may benefit applications for cell-based cancer imaging and therapy including nanoparticle-mediated drug delivery and hyperthermia. Pain and swelling of the soft tissues and an elevated erythrocyte sedimentation rate are characteristics of this seronegative rheumatic disease.

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Short interfering RNAs (siRNAs) represent an exciting new direction for the pharmaceutical industry. Eighty-four patients with clinical findings of hyperactive rhinopathy and no significant septal deviations were treated for 4 weeks with topical applications of capsaicin, which is the pungent substance in hot peppers. These results suggest that plasma ET-1 is related to diabetic microvascular disease. Fasting blood glucose values of patients who underwent liver transplantation because of hepatitis C-related cirrhosis (73 patients) were compared with those of patients with cirrhosis due to cholestatic (78 patients) or alcoholic liver disease (53 patients) and to a general population. In this study we examined the effect of carnitine and acetylcarnitine on the human erythrocyte membrane stability and membrane deformability.

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Here, we evaluate the performance of the TD model with a heretofore unexplored range of classical conditioning tasks. CDW fluctuations and the pseudogap in the single-particle conductivity of quasi-1D Peierls CDW systems: II.