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By combining experimental techniques (optical spectroscopy, HPLC coupled to mass spectrometry) with theoretical methods (molecular dynamics, DFT/TD-DFT calculations in solution), we study trinucleotides with key sequences (TCG/T5mCG) in the UV-induced DNA damage. Failure of adrenocortical extract to modify the immunity acquired by intact mice through the use of pneumococcal vaccine.

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Based on allele-specific oligonucleotide hybridizations, we believe that the hCE and hCEv cDNAs represent two distinct members of the carboxylesterase family. HIV-positive pregnant women would benefit from the scaling up of de-worming programs alongside health education and hygiene interventions. Modifications that preserve the net charge of the hexon protein, or those that cause only a small charge difference in the fiber protein, in addition to shortening the fiber shaft, did not change the chromatographic behavior of the adenovirus particles.

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Still not fully mature however, these are not yet able to cope with the increasing number of quantitative proteomic technologies that are being developed. The substitute may be a lens placed in front of the eye (spectacles), on the surface of the eye (contact lens), or inside the eye (intraocular lens). Fibrinolytic activity and effect of anti-fibrinolytic agents on the growth of cloned cell lines derived from experimental uterine and ovarian adenocarcinomas in rat were studied in tissue culture. Individual variations in food metabolism and energy expenditure may be responsible for much of the adiposity present amongst individuals.

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Relationship between the crystallization rates of amorphous nifedipine, phenobarbital, and flopropione, and their molecular mobility as measured by their enthalpy relaxation and (1)H NMR relaxation times. Image quality depends on factors such as exposure and projection but also on optimum processing of the x-ray film. Mutagenesis and gene cloning in Schizosaccharomyces pombe using nonhomologous plasmid integration and rescue. The influence, on medicine, of progress in the knowledge of subcellular and macromolecular structures

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Functional magnetic resonance imaging (fMRI) studies on humans have identified a region in the left middle fusiform gyrus consistently activated by written words. A method for the morphological identification of contractile filaments in single cells. The aim of the present study was to analyze our experience with a new liquid embolic agent, Squid, for the treatment of cerebral vascular lesions. Transition from positive to neutral in mutation fixation along with continuing rising fitness in thermal adaptive evolution.

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A randomised trial evaluating the effects of the TRPV1 antagonist SB705498 on pruritus induced by histamine, and cowhage challenge in healthy volunteers. Strategies for cellular therapy in the CNS consist primarily in heterologous transplantations. Moreover, caveolin-1 altered TrkA modification including tyrosine-490 phosphorylation and unidentified cleavage(s), resulting in the inhibition of TrkA-induced apoptotic cell death.

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In all the couples a karyotype analysis was carried out including an investigation of C and/or G bands. Future challenge is to define genetic drivers in asthma phenotypes to provide therapeutic targets. In these cases, measurement of the DM/DD ratio can provide a valuable tool in establishing the diagnosis. Polyprotein processing of alphaviruses: N-terminal structural analysis of Semliki Forest virus proteins p62, E3 and ns70.

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Wernicke-Korsakoff syndrome in monozygotic twins: a biochemical peculiarity. Optimal conditions in preparation and application of vaccines from complete antigens. The proscription of milk products during flares of disease by many physicians is not supported by this study. The results regarding their antimicrobial action are also presented.

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A plea for higher-quality data for GreenLight laser technology in the context of surgical benign prostatic obstruction trials: the GOLIATH study-fact or fiction in the era of evidence-based urology? Endometrial cancers from 702 patients recruited into the Australian National Endometrial Cancer Study (ANECS) were tested for MMR protein expression using immunohistochemistry (IHC) and for MLH1 gene promoter methylation in MLH1-deficient cases. We do not know whether this was a technical error, but are inclined to believe it was due to abnormal currents in the aneurysm. The authors describe a case of a basilar trunk aneurysm with long-term follow-up after successful bypass and proximal occlusion.

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Characteristics of vasoinhibitory action of FK 453 (a pyrazolo-pyridine derivative), a new antihypertensive agent with diuretic action in isolated rabbit aorta. Abdominal obesity: role in the pathophysiology of metabolic disease and cardiovascular risk. Following 48 hours of 2,5-dimethoxy-4-iodoamphetamine administration, we found that the liver endothelium in the young, but not in the old, mice had increased porosity compared with controls. The behavior of total proteins and of some serum proteins and lysozyme was studied on purified samples of cervical mucus during the normal menstrual cycle, during pregnancy, and under different conditions of hormonal stimulation. In contrast to the situations with model organisms and parasitic protozoa, progress with gene manipulation with schistosomes has been delayed by impediments that include our inability to maintain the life cycle in vitro, absence of immortalized cell lines, large genome sizes, unavailability of drug resistance markers and other difficulties.