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Birth asphyxia alters neonatal intestinal motility in term neonates. Certain acidic drugs bound to alpha 1-AGP at one binding site with a high affinity. Small molecule inhibitors of the hedgehog signaling pathway for the treatment of cancer. GABA(A) receptor subunit expression within hypophysiotropic CRH neurons: a dual hybridization histochemical study. Nocturnal awakening and sleep efficiency estimation using unobtrusively measured ballistocardiogram.

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English language articles were sought using MEDLINE, CINAHL, Embase and Cochrane and included two previous systematic reviews completed five and seven years ago. A pair of male monozygotic twins discordant for Rubinstein-Taybi syndrome is reported. Lead exposure in starter battery production: investigation of the correlation between air lead and blood lead levels. Dense magnetic arrays formed by electrochemical deposition of nickel over self-limiting formed molds are demonstrated. The voices of elderly nonsingers (NSG) showed significant increase in scores related to the overall degree of deviance and presence of roughness and strain.

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Therefore a model to generate simulated EEG with known spectrum is proposed and the model is used to evaluate performance of several parametric and Fourier based spectral estimators. The SAPS score proposed by Le Gall, was used in 128 patients undergoing biliary surgery between January 1987 and April 1988. Many of the potential health benefits of flavonoids have been associated with their specific chemical and biological properties including their ability to interact and bind non-covalently to macronutrients in foods. Post sex affectionate exchanges promote sexual and relationship satisfaction. But long before synapses are formed in vertebrates, AChE is expressed in young postmitotic neuroblasts that are about to extend the first long tracts.

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Development of neuronal responsiveness in the mediorostral neostriatum/hyperstriatum ventrale during auditory filial imprinting in domestic chicks. Synovial fluid osmolality in osteoarthritis and rheumatoid arthritis. Standardized reporting of long-term neurological sequelae is imperative so that meaningful analysis and study comparisons can be made. Classification and team response to nonroutine events occurring during pediatric trauma resuscitation. To retrospectively evaluate thoracic CT findings in patients with pulmonary cryptococcosis whose immune status ranged from normal to severely compromised, and determine characteristic imaging features of pulmonary cryptococcosis between patients with different immune status.

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Spermatozoa displayed a bigger size when processed with CASMA-F than with HEM method in all primary sperm head morphometric parameters, but results using both methods were correlated. A comparison has been made between the ability of different acridine compounds to act as sensitizers for visible light (400-700 nm) induced chromosomal aberrations and sister-chromatid exchanges (SCE) in unsynchronized Chinese hamster ovary (CHO) cells. Stratification of cases by race yielded even stronger findings and indicated that whites had clustering of cases for several cancer types. Composition of a paraffin wax fraction from tobacco leaf and tobacco smoke.

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Starting from a singleton chromanone high throughput screening (HTS) hit, we describe a focused medicinal chemistry optimization effort leading to the identification of a novel series of phenoxymethyl-dihydrothiazolopyridone derivatives as selective positive allosteric modulators (PAMs) of the metabotropic glutamate 5 (mGlu5) receptor. More than 30 years of clinical application has demonstrated that HC-A is safe and effective. These processes are believed to underlie an important part of cultural variation among human populations and may also explain intraspecific variation in behavior between geographically distinct populations of animals. Cholangioplasty by using a patch of bovine pericardium in the treatment of stricture of extrahepatic bile duct

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The 91-year-old male patient had a recurrent tumor inferior to the temporal lower eyelid 7 months after tumor excision, however, lymph node metastasis is not present as of yet. These data suggest that the actions of ethanol on locomotor activity normally result from the combination of a direct stimulatory effect of ethanol per se and an inhibitory effect of acetate, produced endogenously from ethanol. The decreased levels of receptivity of the PVC animals could be related to a disruption of the LHRH system, while the RPP group responses could reflect a hypersensitivity of remaining neurons to estrogen. We mainly focus on DUX4 isoform expression because the expression of DUX4 has been confirmed in both FSHD cells and biopsies by several laboratories.

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melanogaster, reared on a medium containing 0.01, 0.02 and 0.03 mg/ml of the drug, were screened for sex-linked recessive lethal mutations. More importantly, the inheritance of TGNPs to the daughter cells through mitosis was found to be the major route to metabolize TGNPs by HeLa cells.

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Instrumental and sample considerations that can maximize data quality are discussed along with some details for optimal data acquisition and processing parameters. Physical stability and in-vitro gene expression efficiency of nebulised lipid-peptide-DNA complexes. A qualitative technique with individual in-depth interviews was used. The presence of H8 among EHEC O26 and its stx-negative derivative isolates is described for the first time. This high stability facilitated the crystal structure determination of this receptor and also allowed us to probe the pharmacology of detergent-solubilized, apo-state NTS1 using robotic ligand binding assays.

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Interatrial differences of basal molecular set-up and changes in tachycardia-induced heart failure-a proteomic profiling study. Instrument development and the measurement of unitary constructs. To fully realize the value of this technology, centralized databases that are capable of storing microarray expression data and managing information from a variety of sources will be needed. The calcium taken by the liver cells at 10 min after calcium administration was markedly located into the nuclei, mitochondria and microsomes, and this distribution was not accompanied by a significant elevation in the cytosol level. At the same time, a high degree of variability was observed in the amount and quality of anchoring fibrils in the various stages of lesional skin, including co-existence of normal and partially degraded anchoring fibrils.

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An extended physiological pharmacokinetic model of methadone disposition in the rat: validation and sensitivity analysis. On hypernephromas (latent forms manifested by solitary metastases) Similar postoperative safety between primary and revisional gastric bypass for failed gastric banding.

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Resections of intracranial aneurysms were performed in 10 cases. After the first cycle of cisplatin treatment, early ototoxicity occurs in close to two-thirds of patients, as identified by measuring DPOAE.

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Two patients with hypertrophic osteoarthropathy of unusual aetiology are described. Both lung recruitment maneuvers can effectively improve oxygenation and lung compliance of dogs with severe smoke inhalation injury. We report a case of a 75-year-old man submitted to a rectosigmoidectomy and partial cystectomy because of a sigmoid cancer and colovesical fistula. a mild psychological stress, causing the mood worsening before standard exercise test, does not evoke pronounced alterations in cardio-respiratory responses to exercise in healthy men, but it does affect the magnitude of exercise-induced changes in both plasma free and total noradrenaline concentrations.

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The primary aim of this study was to examine the motor activity (motility) of a gastric tube after laparoscopic-assisted proximal gastrectomy (LPG). Thus, as previously seen for other integrins, the alpha 2 cytoplasmic domain acts as a negative regulator, preventing indiscriminate integrin recruitment into FACs.

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Starch granule numbers and distribution and the accumulation of starch synthase substrates and products were investigated during ss4 leaf development, and in ss4 mutants carrying mutations or transgenes that affect starch turnover or chloroplast volume. We present two cases of acute isoniazid poisoning in patients who ingested 7.5 g and 5.0 g of isoniazid respectively, with the intention of committing suicide. Corticomedullary contrast on T1-weighted images decreased persistently from 1 hr to 2 weeks after ligation. Dose indices for targets and critical organs were compared using dose-volume histograms, BOT, and monitor units.

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It is also postulated that this benefit cannot be achieved when the drug is injected with higher rates thus producing the same high concentration at the site of injection. An improved method for two-dimensional fluorescence monitoring of complex bioreactors. A comparison of Rorschach and Howard tests on a schizophrenic population. Sixteen of the 65 mutations were phenotypically repeat mutations, occurring at 11 loci. Further longitudinal and interventional studies are needed to understand and address the complex relationship between poverty, maternal depression, social safety nets, and food insecurity.

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Such observations suggest that a similar mechanism may be operating in primates since lead intranuclear inclusion bodies are also observed in these species. The survey included six typical clinical cases in children under 5 years with questions about antibiotic use: the cases were common cold, pharyngitis, pneumonia, bronchial obstructive syndrome, watery diarrhea and dysentery.

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Transfusion associated graft-versus-host disease, cytomegalovirus infection and HLA alloimmunization in neonatal and pediatric patients. Bone metastases from CaP are associated with osteoblastic differentiation resulting in abnormal bone formation.

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Comparison of the Ciona model system to heart development in other Chordates presents great potential for dissecting the genetic mechanisms that underlie congenital heart defects and disease at the cellular level and might provide additional insight into potential pathways for therapeutic cardiac regeneration. A broad variety of professionals was identified who perform consumer health education in these health care institutions. M13 core sequence and M13 modified core sequence yielded 5 and 8 PCR types, respectively.

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The nasal and external auditory canal swabs were collected from 83 haemodialysed patients. Integration of functional imaging into treatment planning and image guidance during treatment is expected to further improve the therapeutic ratio. A comprehensive bioinformatics analysis using 12 different sequence-based microRNA target prediction algorithms revealed that 81 out of these 266 down-regulated transcripts are potential direct targets for the miR-99 family. All women were found to have normal personality structure as measured by the Minnesota Multiphasic Personality Inventory (MMPI).

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Silencing of Deaf1 reduced Eif4g3 expression, but increased the expression of Caspase 3, a serine protease that degrades eIF4GII. The results of this study suggest that metoclopramide activates the sympathetic nervous system by mediating the central cholinergic system in humans. Physico-chemical characteristics of endogenous regulatory oligopeptides

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Psoriasis (Pso) has a strong impact on quality of life and a positive association has been reported between nail psoriasis (NP) and more severe disease, together with a longer duration of skin lesions. Protein alterations upon exogenous stimulus are vital in outlining differences that cannot otherwise be measured quantitatively. Inhibition of influenza virus replication in mice by GG167 (4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid) is consistent with extracellular activity of viral neuraminidase (sialidase).

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The targeting efficiency and specificity of SV119 liposomes to cancer cells was demonstrated in vitro. Fresh blood cell deposits could be observed in the unlined prosthetic wall. The purpose of this review is to highlight the impact of MRgFUS on fertility and reproductive outcomes.

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However, this collagen preparation failed (1) to produce joint lesions in rabbits or (2) to exacerbate joint lesions in rabbits formed in the serum sickness model. Modification by environmental chemical factors of the blastomogenesis induced by nitrosodimethylamine Such studies may give a consistent integral view of a wealth of experimental data.

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As in immunocompetent women, high oncogenic risk viral type and multiple infections are associated with a histologically proven cervical intraepithelial lesions. Intramucosal peptic activity may participate in the genesis of acute and chronic superficial gastritis. Future studies on the significance of ISI should ensure use of a uniform grading system, standardized outcome measures and multivariate analyses to control for other preoperative variables. In NaCl-treated seedlings, some protein was detectable after 6 h of treatment and reached maximal levels between 24 and 48 h. Origins of base specificity in actinomycin and other DNA ligands.

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Good survival and pregnancy rates can be achieved after thawing and removal of cryoprotectant and transfers of frozen/thawed bovine embryos to heat synchronized recipients. Wolbachia infection modifies the profile, shuttling and structure of microRNAs in a mosquito cell line. Visual discrimination was studied in each visual field of a patient with surgical section of the posterior corpus callosum.

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The combinations of nifedipine (10 and 20 mg/kg) with valproate (100 mg/kg) or phenobarbital (6.25 mg/kg) resulted in significant protection against pentylenetetrazol-induced seizures. In the presence of succinate, the oxidative phosphorylation chain is required, but only to provide ATP. Effect of light stimulation of the retina on super-weak luminescence of the contralateral eye in man A method of computerized processing of results of the population sample survey within the 1978 general population census