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Esipram (Escitalopram)
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Escitalopram

Esipram is a selective serotonin reuptake inhibitor (SSRI) used for the treatment of major depressive disorder (MDD) and anxiety disorder. This drug exerts a highly selective, potent, and dose-dependent inhibitory effect on the human serotonin transport. By inhibiting the reuptake of serotonin into presynaptic nerve endings, this drug enhances the activity of serotonin in the central nervous system. Esipram also has allosteric activity. Moreover, the possibility of interacting with other drugs is considered low. This review covers randomized, controlled studies that enrolled adult patients with MDD to evaluate the efficacy of Esipram based on the Montgomery–Asberg Depression Rating Scale and the Hamilton Depression Rating Scale. The results showed that Esipram was superior to placebo, and nearly equal or superior to other SSRIs (eg, citalopram, paroxetine, fluoxetine, sertraline) and serotonin-noradrenaline reuptake inhibitors (eg, duloxetine, sustained-release venlafaxine). In addition, with long-term administration, Esipram has shown a preventive effect on MDD relapse and recurrence. Esipram also showed favorable tolerability, and associated adverse events were generally mild and temporary. Discontinuation symptoms were milder with Esipram than with paroxetine. In view of the patient acceptability of Esipram, based on both a meta-analysis and a pooled analysis, this drug was more favorable than other new antidepressants. The findings indicate that Esipram achieved high continuity in antidepressant drug therapy.

Other names for this medication:
Escitalopram, Lexapro, Aramix, Celtium, Cipralex, Citoles, Ectiban, Entact, Esertia, Esipram, Esita, Eslorex, Esram, Gaudium, Lexamil, Lextor, Losiram, Losita, Neozentius, Nexcital, Seroplex, Sipralexa, Tiopram,

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Surgical treatment of aneurysm of transverse aortic arch using cardiopulmonary bypass with selective cerebral perfusion Genotoxicity risk assessment and oocytes: basis of genetic toxicology and application in reproductive science

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Neurologically, sensory impairment below the L1 dermatome of the left leg, and motor weakness of bilateral legs were noted on admission. Interactions between the two regions during the intertrial interval are associated with decision inertia on a subsequent trial. We revealed that all these alterations can occur independently from each other.

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Staphylococcus aureus and enterobacter are the two most common organisms responsible for infected peripheral aneurysms. However, the pediatric population has an additional factor to consider, namely the ontogeny of gene expression which may result in variation throughout growth and development.

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Quantitative histochemical studies evaluated the extent of sinus disease and gland density in the middle turbinates. The effect of social capital on the use of general practitioners: a comparison of immigrants and non-immigrants in Ontario.

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Histopathological investigation of experimental ocular toxocariasis in gerbils. In detail, GAPDH was up regulated, but HPRT1 and HMBS were down regulated at high density and under hypoxia. A low-methionine diet might offer a perspective for reversing the metabolic imbalance in DS, but this awaits clinical investigations.

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No hematologic or renal toxicity was observed with the above schedule. The assignment of haplogroups to mitochondrial DNA haplotypes contributes substantial value for quality control, not only in forensic genetics but also in population and medical genetics. The University of Kansas Medical Center and Quinn Plastic Surgery Center, both in the midwestern United States. To evaluate the presence of symptoms of inattention and hyperactivity/impulsivity in a population of school age children affected by vocal fold nodules. Bronchial stenosis (middle lobe, lateral division) produced by calcified tuberculous lymph nodes.

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Majors with higher mean NCEE scores had higher mean GPAs, and higher GPAs were observed among those individuals with higher NCEE scores after controlling for major-level characteristics. We report a high STI prevalence among adolescents attending public high schools, in the District of Panama. This technique transfers segmentations from expert-labeled images, called atlases, to a novel image using deformable image registration. Morphological and cytological changes in microscopic fungi using dendrodochine as a substrate

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The main outcomes were distribution of locations, response rate, rebound growth rate, spherical and cylinder power before and after treatment, amblyopia rate and adverse events. Personal, team, and institutional aspects emerge as reasons behind the experience of these issues.

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Changes in ghrelin concentrations across the day after weight loss are closely associated with other physiological adaptations to energy deficiency, further supporting the role of ghrelin as a countermeasure to restore energy balance. Despite the hyperinsulinaemia, hepatic glucose production was higher in the Aboriginal subjects (P less than 0.01), while metabolic clearance rate was lower. Curcumin sensitizes glioblastoma to temozolomide by simultaneously generating ROS and disrupting AKT/mTOR signaling. We proposed a new stent with streamlined cross-sectional wires, which is different from the clinical coronary stents with square or round cross-sections. DBS may show promise for treatment-resistant OCD but there are insufficient randomized controlled data for other psychiatric conditions.

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The progression of dementia is associated with an increasing demand for patient care. The following points were evaluated: clinical features, and hematological, biochemical and microbiological reports, imaging findings and the role of therapeutic modalities like percutaneous aspiration (single or multiple), catheter drainage and operative drainage (transperitoneal, extraperitoneal and percutaneous).

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In the retina, the direction of image motion is computed in four cardinal directions, but it is not known at which circuit location along the flow of visual information the cardinal direction selectivity first appears. A retrospective cohort analysis was done using data on MDR-TB patients diagnosed during 2009-2012 under Revised National Tuberculosis Control Programme at the institute. In this review, it is argued that each compensatory mechanism leads to overcompensation and that there is no way to distinguish between the beneficial aspects of the former and the harmful effects of the latter. Significant improvements in magnetic field gradient waveform fidelity after pre-equalization have been realized and are summarized.

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These findings have potential applications for depression prevention programs in target populations with similar social and cultural contexts. Detection and management of congenital dysplasia and dislocation of the hip in neonates and infants Estrogen stimulates the proliferation of human endometrial cancer cells by stabilizing nucleophosmin/B23 (NPM/B23).

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Endothelial progenitor cells augment collateralization and hemodynamic rescue in a model of chronic cerebral ischemia. The author concludes that the NEP has had relatively little impact on either reducing fertility or achieving income equity.

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The morphological events, as monitored by the electron microscope, of the reversion to the intact bacterial phase of an unstable L-phase variant of B. International Multisensory Research Forum 2012 meeting special issue. Occurrence of three haplotypes of Linepithema micans (Forel) (Hymenoptera: Formicidae) in Southern Brazil. Illusion-related brain activations: a new virtual reality mirror box system for use during functional magnetic resonance imaging. Histological diagnosis was reported as osseous cavernous hemangioma.

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Using demographic and epidemiologic data from the GBD 2010 STUDY, we calculated the potential decrease in burden of digestive diseases if quality surgical services were available universally and accessible at first-level hospitals. The majority of the examinees retained biochemical signs of cholestatic, mesenchymal-inflammatory and moderate cytolytic syndromes secondary to hepatic impairment.

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However, characterization of invadopodia using these methods has traditionally been done manually with time-consuming and potentially biased quantification methods, limiting the number of experiments and the quantity of data that can be analysed. In general, the evidence at present is limited and much additional research will be necessary for a complete understanding of this relationship. Combination treatment with decitabine and ionizing radiation enhances tumor cells susceptibility of T cells. Several hypotheses are discussed on the possible role(s) of porcine embryonic IFNs at the initial stages of gestation.

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One topic will be the classification of the etiological agent which changed several times since the first description in 1906 and was most recently modified again. Apart from its role in the coagulation system, thrombin plays an important role in the inflammatory response through its protease-activated receptors (PARs). In the present study, a case of primary, non-functional adrenocortical carcinosarcoma is described, as well as a review of the literature to raise awareness of this particularly rare type of malignant neoplasm that is associated with a worse diagnosis and prognosis than adrenocortical carcinoma. Data for the distribution of MICs and clinical outcomes were analyzed in this study to evaluate the impact of changes in the CLSI breakpoints on the treatment of Klebsiella pneumoniae bacteremia. Intravenous amiodarone in atrial fibrillation complicating myocardial infarction.

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The porphyrias are heterogeneous disorders arising from predominantly inherited catalytic deficiencies of specific enzymes along the heme biosynthetic pathway. As in Venezuela only the clinical analysis are performed in HCM patients, we decided to search for genetic variations in the MYH7 gene. Second, we report that the fluorescence of tyrosinamide-oligosaccharides allows their sensitive detection (5 pmol) on HPLC.

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Changes in dopamine (DA) signaling have been implicated in a number of human neurologic and psychiatric disorders. Contribution of the microbial communities detected on an oil painting on canvas to its biodeterioration. Microanalysis of enzyme digests of hyaluronan and chondroitin/dermatan sulfate by fluorophore-assisted carbohydrate electrophoresis (FACE). Each color sample from all shade guides was measured three times and the basic parameters of color quality were examined: deltaL, deltaC, deltaH, deltaE, deltaElc.

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Patch testing is only 1 element in the assessment of causation in those with postimplantation morbidity. A method of identifying problems and of detecting diagnostic deficiencies by using the primary care center information system 20 dogs with urolithiasis treated by laparoscopic-assisted cystotomy and 23 dogs treated by open cystotomy. Using realist evaluation, data collection included documentation (e.g.

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Participants included 169 children, 4-6 years old, attending either preschool or an afterschool program. Noncompliance of high-risk pregnant women in keeping appointments at an obstetric complications clinic.

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MSCs can be expanded in vitro and have potential for differentiation into multiple cell lineages. Data of death for persons who died in the city of Arkhangelsk in the period from 1 July 2011 to 30 June 2012 (one year) were copied out. Evaluation of perfusion technics of the magnocellular nucleus of the hypothalamus in vitro and in vivo Hyperpalatable Diet and Physical Exercise Modulate the Expression of the Glial Monocarboxylate Transporters MCT1 and 4. Current management for patients with differentiated thyroid cancer includes near total thyroidectomy and radioactive iodine therapy followed by administration of supraphysiological doses of levothyroxine (L-T4).

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ALA-induced porphyrin formation and fluorescence in synovitis tissue In-vitro and in vivo studies. In lithium-ion batteries (LIBs) comprising spinel cathode materials, the dissolution of transition metals (TMs) in the cathodes causes severe cyclic degradation. The influence of HES on the filtration properties of capillary membrane plasmaseparation. In the reaction of cisPt and Z-DNA, a monodentate adduct is formed. Census-based approaches for studying aggregate changes in characteristics of the elderly.

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A model for understanding the manner in which genes and hormones may interact to influence infanticide and other hormone dependent sexually-dimorphic behaviors in mice is presented. Our analysis revealed that ticks are reservoirs for a wide range of viruses and suggests that discovery and characterization of tick-borne viruses will have implications for viral taxonomy and may provide insight into tick-transmitted diseases.

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The hormonal environment induced by this therapy was similar to that of ovulating women, as demonstrated by serum levels of estradiol, endometrial histology and pituitary gonadotropin secretion before and after LH-RH double stimulation. Using birth control pills for postcoital contraception is not an indication approved by the US Food and Drug Administration, but physicians are allowed to prescribe any labeled drug for unlabeled purposes if they believe it is necessary.

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Bone-marrow-derived mesenchymal stem cells (BMSCs) represent an attractive cell source for therapeutic applications involving tissue engineering, although disadvantages, such as pain of harvest and low proliferation efficiency, are major limitations to the application of BMSCs in the clinic. Excretion rate and volume appear to be the factors which are most responsible for the inability of the whole animal to maintain homeostasis in cholesterol concentration when a large amount is consumed. Each group was then allowed and encouraged to use the other resource and then asked about their preferences for type of resource at the end of term. The results of this study demonstrate that SATB1 expression in CRC is significantly associated with beta-catenin overexpression, microsatellite stability and SATB2 expression. The data suggest that EP3 receptor are potential targets in the treatment of diabetes induced underactive bladder.

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The 1986 Test of Adjustment Related Operations in Central Los Angeles County Sequence analysis of the two positive clones showed that the variable heavy domains (VH) and variable light domains (VL) were highly homologous with the registered murine Ig heavy chain V region sequences and kappa light chain sequences, respectively. Significance of plant metabolism in the mutagenicity and toxicity of pesticides. Monetary contracts in weight control: effectiveness of group and individual contracts of varying size.

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The use of closed suction drains in the abdominal wall is a common practice in abdominal wall reconstruction (AWR) operations. Amino acid alterations in the benA (beta-tubulin) gene of Aspergillus nidulans that confer benomyl resistance. An autopsy case showing massive fibrinoid necrosis of the portal tracts of the liver with cholangiographic findings similar to those of primary sclerosing cholangitis.

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chemoradiation in T2-4aN0M0 bladder cancer: a case-control study. Setting a research agenda for progressive multiple sclerosis: the International Collaborative on Progressive MS.

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Standardization of pathoanatomic activities in performing specialized and high-tech morphological studies A 5 year old child, previously diagnosed as having tetralogy of Fallot, was admitted to hospital in severe congestive heart failure. The role of first trimester screening was found effective in reducing adverse maternal and perinatal outcomes in GDM.

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However, the incidence of menstrual symptoms in adult women was not significantly related to preparation for menstruation or to whether or not menarche was a positive event. Eighty-eight children who were discovered to have vesicoureteral reflux were prospectively studied over a two-year period. The utilization of spectral subtraction improved the accuracy of the SWE as compared to energy thresholding. Sympathetic social support makes a vital contribution to the mourning process, the study showed. The development of myiasis was facilitated by the mental and physical debility and dependency of the patient, numerous and deep facial necrotic wounds and a lengthy period of hot weather which led to prolonged open window ventilation of his room.

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A detailed description of the experimental apparatus is offered. The significance of medical cooperation in maxillary orthopedic prophylaxis Protection from nonsteroidal anti-inflammatory drug (NSAID)-induced gastric ulcers by dietary nitrate. This final rule also clarifies how hospices are to report diagnoses on hospice claims, and provides updates to the public on hospice payment reform.

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Clinically, the quality and vitality of the recipient bone defect is of great importance. TS and DPD were moderately expressed in penile cancer and their expressions were positively correlated. The present article provides an overview of previous studies with injectable PLLA, and specifically focuses on the number of recommended treatment sessions and intervals between treatment sessions. Effect of percutaneous renal denervation on blood pressure level and sympathetic activity in a patient with polycystic kidney disease. Antibacterial activity of Aquilaria crassna leaf extract against Staphylococcus epidermidis by disruption of cell wall.

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All patients less than 18 years of age who underwent trabeculectomy with MMC from June 1991 through October 1997 were included. Spectra collected were subjected to both empirical and multivariate analytical techniques. Diabetic children, but not their siblings, were taller than control subjects before diagnosis, suggesting growth-inducing metabolic changes may precede the onset of clinical diabetes by at least 3 yr.

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Preincubation of atria for 30 min with the noradrenaline uptake blocker desimipramine (DMI, 10(-6) M) or with the beta-blocker propranolol (10(-7) M), abolished the positive chronotropic action of az-DSP4. The study found that factors about the layout design affect judgment performance. The modular structures of repeat proteins afford them distinct properties compared with globular proteins, enabling them to function in a large and diverse range of cellular processes.

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It was found many years after lumbar spine operation, although the patient had confusing symptoms during the whole period. A method for evaluating chemical selectivity of agonists for glutamate receptor channels incorporated in liposomes based on an agonist-induced ion flux measured by ion-selective electrodes. Other animals were injected with one or four doses of NPH, on as many days, or diluent alone, and pretreated by bilateral intra-DMV administration of graded doses of ORX-A or vehicle on the final day of the study.

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Open reduction and internal fixation also decrease the soft tissue complications and frequent follow-up required with functional bracing. Development of a novel iPad-based laparoscopic trainer and comparison with a standard laparoscopic trainer for basic laparoscopic skills testing. Energy intake goal was reached earlier in a higher proportion of patients. Vitamin D deficiency and hyperparathyroidism with severe bone disease.

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Profiling nitric oxide metabolites in patients with idiopathic pulmonary arterial hypertension. Incorporation of scattered radiation into dual-energy radiologic theory and application to mammography.

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Here we show that the bupropion-induced increased locomotor activity found in wild-type animals was no longer observed in HD mice. The role of glucose in preventing stress gastric mucosal injury. Recent advances strongly suggest that mRNA rather than DNA will be the nucleotide basis for a new class of vaccines and drugs.

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To verify the occurrence of natural variations in thigh and abdominal subcutaneous fat thickness related to the phases of the menstrual cycle, to assess the value of ultrasonography as a reliable method for monitoring subcutaneous fat thickness changes and to evaluate their amplitudes. The purpose of this study was to determine the frequency and distribution of the various outcome instruments used in the foot and ankle literature, and to identify trends for use of these instruments over time. Cross-sectional data from the Epidemiology of Diabetes Complications Study were used to examine the associations between WHR and risk factors for IDDM complications such as lipid or lipoprotein levels, blood pressure and fibrinogen. Our findings provide critical insights into disease pathology, and will help guide future preclinical studies aimed at testing the effects of potential therapeutic agents on the onset and progression of TDP-43 proteinopathies.

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We demonstrate that the clarithromycin 500mg capsules maintenance phase of long-term potentiation (LTP) is blocked by local application of exogenous NGF in rat visual cortex at an early stage of postnatal development. Fifteen postnatally confirmed cases of prenatally diagnosed cephaloceles and two misdiagnosed cases were identified. Alteration of the action potential of tissue cultured neuronal cells by growth in the presence of a polyunsaturated fatty acid. An event is defined by two double strand breaks (DSB) on the same or different chromosomes.

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The effect of microinfusion of the N-methyl-D-aspartate (NMDA) antagonist 2-amino-5-phosphonopentanoic acid (AP-5) into the amygdala, medial prefrontal cortex, and dorsal and ventral subiculum on acquisition of a lever-pressing task for food in rats was examined. Proteomic analyses revealed that VCs promote renavit patient information leaflet tamsulosin global changes in the expression of proteins involved in photosynthesis, starch metabolism, and growth that can account for the observed responses in pgi1-2 plants. This study seeks to characterize the types and patterns of data usage from EHRs for clinical research.

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Swine pepsinogen folding intermediates are highly structured, motile molecules. Ischemic heart disease is a common cause of out-of-hospital cardiac arrest (OHCA). Clinical, neuropsychological and radiological signs were studied in a patient suffering from pure alexia associated with vigora capsule female anatomy right superior quadrantanopia. A full history and examination will provide a diagnosis in most cases.

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These and other empirically founded approaches can be landmarks for the revision of this section in Diagnostic and statistical manual for mental disorders-V and International classification of diseases-11. Neurologic impairment--epilepsy, psychomotor retardation, and/or electroencephalographic abnormalities--was present in over one half of the patients. To realized the role of H1 receptor involved in TF-induced apoptosis, different H1 receptor antagonists including promethazine, mequitazine, and chlorpheniramin (50-100 microM) were administered and demonstrated that these chemicals cannot induced apoptosis through the H1 receptor signaling pathway. Limited access to health services along with inadequate knowledge of slum spirolang per acne rosacea residents about health care facilities was the main barrier to the utilization of the health care in the slums. This paper discusses back-projection using auxiliary data on AIDS cases, particularly the time of first positive HIV test.

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We studied ultrastructure of synaptic connections between long-living dentate fascia transplants and somatosensory area of the neocortex in rats. Thus, C(2)H(4) has two binding sites, and the presence of CO affects only the site at which it binds as a substrate. The constant nature of levofloxacin skin rash photo the carrier fluid and channel configuration for this technique eliminates many variables associated with multidimensional analysis. Given the importance of promoting cessation among pregnant women, future campaigns could make greater use of emotional appeals and place less emphasis on informational approaches, which often prompt vigorous counter-arguments. Urologists who participated in a prospective clinical study were sent a retrospective questionnaire to assess the value of the CCP test result.

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The purpose of this study was to assess possible gender differences in the prevalence of vocal fry in the voices of young male college students. This study analyzes health inequalities among older adults pantoprazole 40 mg gastro-resistant tablets for toddlers in Spain by adopting a conceptual framework that globally considers two dimensions of health determinants (gender and the socioeconomic development of the region of residence) and the mediating influence of social support, taking into account individual socioeconomic position. Given the rising number of bariatric procedures, we discuss the importance of recognizing thiamine-deficiency in these patients. Nonetheless, we found that the current iteration of da Vinci was not well suited to a lateral to medial (LtM) dissection of the colonic mesentery. Internal Resonance in a Vibrating Beam: A Zoo of Nonlinear Resonance Peaks.