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Thymic innervation in the rat: a light and electron microscopical study. The activities of four mixed function oxidases also were reduced significantly in the liver of rats with portal vein ligation, the changes being greatest for ethylmorphine N-demethylase, a prototype substrate for the phenobarbital-inducible isoenzyme of cytochrome P450. During digestion, lipids undergo modifications of their colloidal and molecular structures, which depend on the digestive conditions and the composition of the digestive juices.

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The Adc/Lmb System Mediates Zinc Acquisition in Streptococcus agalactiae and Contributes to Bacterial Growth and Survival. In this work we have demonstrated that physiological concentrations of caffeine reduce the proliferation rate of H460 cells: along with the modulation of p53, pAKT and Cyclin D1, caffeine also determines a significant FHC up-regulation through the activation of its transcriptional efficiency. use Wiskott-Aldrich syndrome as a model disease and establish that the Wiskott-Aldrich gene product (WASP) serves an essential role in T regulatory cells to contain Th2 effector cell differentiation and prevent allergic sensitization to dietary antigens.

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If we conduct an association test by treating all cases as a single group, we maximize our chance of finding genetic risk factors with a homogeneous effect, regardless of the underlying disease etiology. Cerebral lesions responsible for death of patients with active rheumatic fever. Future research directions in the area of stress and AD are discussed. While this randomized phase II trial met its primary endpoint of PFS at 4 months, other parameters such as response rate and overall survival suggest that the addition of CBP501 does not improve the efficacy of standard chemotherapy for MPM. Much of the disparity is due to the method of assessing vocal cord function.

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Acidic conditions are known to cause desialylation, thus requiring a great deal of attention to sample preparation. While not clarifying the deep history of fire use, our results highlight the long-term stability of the genes under consideration despite major changes in the hominin dietary niche. Polarity and the inherent rules of human developmental changes are defined as perpetually valid aspects of wisdom and are set off against the perpetually changing frontiers of knowledge with their limited validity. Pathomorphologic changes and clinical consequences of retrograde imaging of the pancreatic ducts in necrotizing pancreatitis

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Isolation and characterization of a laminin-binding protein from rat and chick muscle. We undertook a qualitative review of studies retrieved from MEDLINE, EMBASE, and PubMed, and supplemented that process with a hand search of references and abstracts in the literature.

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Our data suggest the immunogenicity of survivin antigen in multiple myeloma and that immunotherapeutic strategies using survivin as a target antigen might be an option for patients with this disease. Hematological toxicity associated with tiazofurin-influence on erythropoiesis. These results indicate that the activation of Ihh signaling may be correlated with pathological changes of condylar cartilage in adjuvant-induced TMJOA. This study aimed to identify whether previous dental treatment is a risk factor for development of vCJD.

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Incapsulation of foreign body by ectodermal epithelium in Rana ridibunda Grating, vernier, and letter acuities were compared in 25 patients with retinitis pigmentosa (RP), whose Snellen visual acuities were better than 20/40, to address the mechanism of visual acuity loss.

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Modern telecommunication technology enables medical information and images to be transmitted from the general practitioner to a hospital or between hospitals. In the current study approaching the ganglion through an incision over the zygomatic arch provided clear exposure of the ganglion and stimulation of the ganglion with that approach led to vasodilatation. We stress the importance of suspecting vitamin B6-dependent streptococci, even when gram stains may suggest presence of other microorganisms. We demonstrated that Aza decreases de novo aortic aneurysm formation from an average aneurysm severity score of 2.1 (control group) to 0.6 (Aza group), and that Aza effectively delays aorta pathology in a progression experiment, resulting in a reduced severity score from 2.8 to 1.7 in Aza-treated mice.

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(1) To assess the efficacy of ECG criteria to screen for left ventricular hypertrophy in comparison to echocardiography. To determine whether expression of the human CETP transgene protects against diet-induced atherosclerosis in SR-BI deficient mice. Using recordings of field potentials, we investigated the pharmacological effects of the clinically employed standard anticonvulsant drugs phenytoin (PHT), carbamazepine (CBZ), valproic acid (VPA) and phenobarbital (PHB) and those of pentobarbital (PB) on 4-AP-induced epileptiform activity.

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Given the cross-sectional nature of this study and the small number of eyes evaluated, definitive conclusions regarding this progression cannot be determined with certainty. Histologic assessment was based on Ishak fibrosis staging for fibrosis and Knodell histologic activity index (HAI) for necroinflammation. In addition, glycyrol suppressed tumor growth in a nude mouse tumor xenograft model bearing HCT 116 cells. A better alternative would use multi-purpose auxiliaries who are more extensively trained than the existing paramedicals but less than doctors.

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Results implicate geology as a primary factor influencing ecological diversification, and sexual selection as a mechanism reinforcing reproductive isolation in areas of secondary contact. Factors considered include increases in immigration, extension of working life, female employment, and increased productivity. Tamoxifen plays a major role in the management of breast cancer in women and is currently used to a lesser extent in other neoplasias.

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It may be possible to delay the step-by-step progression towards frank invasive cancer by avoiding one or more of the well-known clinical risk factors. A major preoperative consideration then is the choice of an appropriate recipient site for revascularizing the flap that is outside the zone of injury, and preferably avoids the need for vein grafts. Following the second transtympanic challenge, the ventilatory and clearance functions of the eustachian tube (ET) were assessed at 0, 2, and 8 hours.

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Most of the mutagenic or co-mutagenic effects of micronutrients observed in vitro can be attributed to their involvement in the generation of oxygen radicals. Reconstruction has provided an acceptable functional and cosmetic result. Powerspectral analysis in the EEG revealed significantly increased alpha-frequencies and heart-rates during the luteal phase of the menstrual cycle whereas the mean theta-frequency and power decreased. Prospective studies are needed to evaluate whether such further classification of morbid obesity could stratify the cardiovascular risk in these patients more accurately.

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To demonstrate the technical feasibility of laparoscopic aortorenal bypass in an acute porcine model. In this case report, the treatment of severe nausea and vomiting caused by acute viral gastritis in a pediatric patient is described, and a formulation for an effective transdermal compound is provided. Cytological definition of the poriferan stylocyte: a cell type characterized by an intranuclear crystal. Twin analyses estimated heritability of BMI-SDS at each age and the longitudinal genetic correlation. Gatifloxacin is effective for patients with acute bacterial rhinosinusitis in the community.

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Based on a single study, there does not seem to be a statistical difference in efficacy between the on-demand versus continuous use of NSAID in the context of ankylosing spondylitis. We sought to determine whether body mass index (BMI) differentially modified the effect of transplant procedure type on 90-day mortality in IPF patients. The role of an academic department of anaesthesia within a community of specialist anaesthetists is discussed. Estimate of the maximum strength of metallic glasses from finite deformation theory.

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Genetic diversity contained in one initial spore repeatedly gave rise to genetically different variants of the fungus with novel phenotypes. Improved adjuvants and delivery systems are needed to boost the immune response. Metacaspase type-1 was identified in Acanthamoeba castellanii, an opportunistic protozoan parasite that causes severe diseases in humans.

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The data show that DBTCl adversely affects the initiation and maintenance of pregnancy when administered during early pregnancy in mice and suggest that the decline in serum progesterone levels is responsible for pregnancy failure. Effect of dose and food on the bioavailability of cefuroxime axetil. MRI can be used to monitor progression of atherosclerosis and differentiate plaque components. Long profiles of subsurface cisterns constituted prominent cytoplasmic features, and these were most conspicuous in the regions of soma-somatic apposition. Photoselective vaporization of prostate (PVP) by 120W HPS laser emerged as an efficient, bloodless, and durable first line alternative to transurethral resection of prostate for treatment of lower urinary tract symptoms (LUTS) secondary to benign prostatic enlargement (BPE).

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pestis infection is mainly determined by the initial level of the activity of oxygen-sensitive cytocidal systems of neutrophils (determined in the nitro blue tetrazolium spontaneous reduction test). To investigate the damage within the ventroposterior nucleus (VPN) of the thalamus after focal cortical infarction and its mechanism, and explore the effect of ebselen on the oxidative damage after cerebral cortex infarction in hypertensive rats. Subclinical mastitis losses are calculated on the basis of lost milk estimates for California Mastitis Test evaluations. Comparative Analysis of Light-Harvesting Antennae and State Transition in chlorina and cpSRP Mutants.

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Effects of single injections of bovine follicular fluid on gonadotrophin concentrations throughout the oestrous cycle of the rat. Arundo donax L., common name giant cane or giant reed, is a plant that grows spontaneously in different kinds of environments and that it is widespread in temperate and hot areas all over the world. Re-emerging malaria in the WHO European region: control priorities and constraints.

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Although not the most common cause, drug therapy does cause changes in cognition, emotion, or behavior in HIV-infected patients. Based on such relationship, a novel paradigm is suggested in order to confirm that the protein interaction networks can be the target of therapy for treatment of complex multi-genic diseases rather than individual molecules with disrespect the network. A ribosomal DNA-polymerase chain reaction (PCR) method has been developed for species identification of individuals of the five most widespread members of the Anopheles gambiae complex, a group of morphologically indistinguishable sibling mosquito species that includes the major vectors of malaria in Africa.

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To obtain a comprehensive map of the brainstem and spinal cord areas that project to the mesencephalic central gray small injections of horseradish peroxidase were made into various regions of the periaqueductal gray in a series of monkeys. Determination by capillary zone electrophoresis of berenil, phenamidine, diampron and dibromopropamidine in serum and urine.

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There is no evidence to suggest that the degree of cerebellar tonsillar descent and syrinx patterns have an effect on the progress of scoliosis and the frequency of atypical curves. We found that, unlike Coffea, the Rhazya lineage has experienced many structural rearrangements. Cytokine-mediated alterations in host metabolism prevent nutritional repletion in cachectic cancer patients.

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Comprehensive comparisons of RsmE with closely related MTases, combined with the biochemical experiments, indicated that the MTase domain of one subunit in dimeric RsmE is responsible for binding of one AdoMet molecule and catalytic process while the PUA-like domain in the other subunit is mainly responsible for recognition of one substrate molecule (the ribosomal RNA fragment and ribosomal protein complex). In susceptible Arabidopsis plants, XopAC type III effector inhibits by uridylylation positive regulators of the PAMP-triggered immunity such as the receptor-like cytoplasmic kinases (RLCK) BIK1 and PBL1. No linear dose-response line was obtained between the toxin dose and hemolysis ratio. We show that the Cullin 3 (Cul3) substrate adaptor KLHL20 is localized to the trans-Golgi network (TGN) and is important for post-Golgi trafficking by promoting the biogenesis of TGN-derived transport carriers.

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Anesthesia and the chemotaxis of neutrophilic granulocytes in newborn infants To investigate real pictures of prescription behaviours of office-based doctors in Korea, especially focusing on the prescription of oral antibiotics and injections. Although there are subtle differences in potentially lignocellulolytic taxa between GPC- and GWC-derived communities, these differences do not affect the decomposition rates for these communities on switchgrass or eucalyptus. Effects of oxygen on cell turnover and expression of regulators of apoptosis in human placental trophoblast. From a total of 51 criteria assessing 9 postures, 1 was rejected.

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Clinical trial to determine the effect of omeprazole given once or twice daily on gastric ulceration. However, contemporary results show a lower than expected prevalence of AAA, thus questioning the benefit of screening. Short latency inhibition of human hand motor cortex by somatosensory input from the hand. Using multiple logistics regression, we predicted probability of being hypertensive for participants ages 15-65 years in the National Health and Nutrition Examination Survey (NHANES) IV, 1999-2002.

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A water molecule now moves into the putative oxyanion hole that is constituted of a main-chain amide (Ser-201) and two conserved side chains (His-150 and Asn-154). Overall we found ID definitions and specified standardized mortality rates and impact of institutionalization to be quite poorly presented.

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A remarkable latency prolongation was observed for condensation (C) compared with rarefaction (R), if a sharp bend at the foot of the slope was avoided. In addition, the ABC algorithm is also introduced to find out the optimal decoupling schemes. Protection of liver function in thioacetamide poisoned rats by heparinoids. Estimation of optical properties by spatially resolved reflectance spectroscopy in the subdiffusive regime. Goat immunoglobulin purification on phosphocellulose and DEAE Affi-Gel blue.

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The screening from the Traditional Chinese Medicine (TCM) database by simulating molecular docking and molecular dynamics could select candidate compounds, which may express MX2 against HIV. Proteomic exploration of the impacts of pomegranate fruit juice on the global gene expression of prostate cancer cell. IgA and serum albumin outputs obtained under the occluding balloon were compared with those found with the triple non-occlusive method. Gamma Knife surgery for intracranial chordoma and chondrosarcoma: radiosurgical perspectives and treatment outcomes.

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This effect was, however, absent when the operation was performed at later stages, and both the otoscopic and audiological findings after five years revealed no significant differences between the adenoidectomy and nonadenoidectomy groups. Mechanisms of cyst formation after radiosurgery for intracranial arteriovenous malformations. Maximizing setup accuracy using portal images as applied to a conformal boost technique for prostatic cancer.

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Although metastases of NTMs to the thyroid gland are uncommon in clinical practice, it should be considered in patients with a history of prior malignancy and a new thyroid mass. Both in older subjects and in those with borderline hypertension the loss of distensibility is most pronounced in the carotid artery bulb, while in borderline hypertensives the proximal part of the bulb, where the baroreceptors are predominantly located, is more affected than other parts of the bulb. The circulating ketone bodies may then be utilized by brain, allowing an increased brain energy reserve and a greater tolerance to a transient stimulation which would have, without Valproate, triggered an epileptic seizure. Thirty-seven ASA Physical Status I parturients undergoing elective cesarean delivery were evaluated to determine the effects of subarachnoid sufentanil administration.

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In 129 of 4757 gene-trap lines, beta-glucuronidase (GUS) activity was detected in some tissue. To determine the expected duration of symptoms of common respiratory tract infections in children in primary and emergency care. Particularly, the amino acids Val/Ile(6.54) in TMD VI and Pro/Glu(7.29) in ECL3 appear to be involved in this activity, since double mutation of these amino acids completely blocked signaling activity while maintaining ligand binding activity. parasitica regulate a gene associated with pathogenicity in other plant-pathogenic fungi.

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ASA class is a robust tool which is predictive of mortality in the very elderly population and can be used to guide patient and family counseling in the emergency setting. Moreover, it is not known when during processing the decision about the temporal order of two stimuli is made. Radiobiology of the skin: review of some effects on epidermis and hair. Factors predicting postoperative hyponatremia and efficacy of hyponatremia management strategies after more than 1000 pituitary operations.

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The impact of mortality declines on Japanese marriage patterns is analyzed for the period from 1965 to 1985 using the life table method. Subarachnoid drainage of an established or chronic pseudomeningocele.

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Microarray and quantitative PCR were used to identify differentially expressed genes both before and after differentiation, thus allowing a precise phenotypic analysis of the two populations. RT-PCR analysis showed that mRNA of galanin and GalR2 were detected in the taste bud-containing epithelium of the circumvallate papilla of rats. The chromatographic separation of P4 and its metabolite, 20alpha-OHP, in rat and buffalo cow serum samples were performed on reverse phase HPLC system.

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A thin-film multiple-electrode probe for measuring de potentials at eight sites with interdistances of 1 mm was constructed for the investigation of slow potential changes in deep regions of the human brain during surgery. Ovulation was achieved in 3 patients, but with insufficient luteal function.