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Endoproteolytic cleavage of its propeptide is a prerequisite for efficient transport of furin out of the endoplasmic reticulum. Oxygen equilibrium studies of Hb Willamette alpha 2 beta (2)51(D2)Pro leads to Arg. A pH-membrane electrode with n-tridodecylamine (TDDA) as the hydrogen-ion-selective ionophore was used for the construction of a potentiometric biosensor for urea determination. Glomerulus infiltration with inflammatory cells, glomerulus cell proliferation, heterogeneous composition and localization of the immune complex depositions even within one morphological form are characteristic of inflammatory glomerulopathies. As a liver biopsy is by far the most reliable method of detecting liver disease, we suggest that it is still of value to include a baseline liver biopsy in the pretreatment assessment of patients even when only a short course of MTX is planned.

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A total of 17,537 respondents aged 18-60 and resident in Edinburgh and Glasgow were interviewed between January 1989 and May 1992 as part of a large scale continuous monitoring survey of lifestyles and health. Furthermore, compared with the wild type, stationary populations of the MTase-deficient E.

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One of the vaccines (coded vaccine B) produced significantly higher vaccine virus heterogeneity in vaccinated chickens than the other vaccine (coded A). Intrauterine infusions every four hours of PGE2 (500 mug) from days 10 to 17 postestrus maintained luteal function only when infused into a uterine horn adjacent to a luteal-bearing ovary of unilaterally ovariectomized sheep with surgically separated uterine cornua. ADAM17 substrate release in proximal tubule drives kidney fibrosis. Fractures of the radial head--the benefit of aspiration: a prospective controlled trial. Rapunzel syndrome: a rare presentation with giant gastric ulcer.

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The breast cancer-associated stromelysin-3 gene is expressed during mouse mammary gland apoptosis. Immunoglobulin-secreting cells were detected by a haemolytic plaque assay using protein-A-coated erythrocytes in the presence of class- or type-specific rabbit anti-human immunoglobulin antisera. Quantification of the depressive effects of diazepam on the guinea pig righting reflex. Migration of the population to Kosice in 1961-1970 and its influence on the age structure of the population Control of hypertension after roux-en-y gastric bypass among obese diabetic patients.

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This article describes CKD staging in the geriatric population and several common clinical presentations of renal disease. In the experimental model of coronary microembolization in pig hearts, the processes of wound healing and scar formation were studied. Here we review transcriptomic analysis as a powerful tool for understanding venom profile, variation and evolution. Within the limitations of a small sample population, the results of this pilot study suggest that not packing the perianal abscess cavity after incision and drainage is safe. A theoretical model for ionic polymer networks describes the observed optical response well and can be used to quantify the extent of phosphorylation.

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Symptoms compatible with vertebrobasilar ischemia have been reported in patients with unilateral or bilateral carotid occlusive disease. The epicardial coronary arteries of 111 patients, who had positive stress tests for ischaemia based on ST/T configurational changes alone but were considered non-ischaemic when the ST/T time-course behaviour was analysed, were assessed. Strength of fertility motivation and contraceptive use in Nepal. A real-time LPC-based vocal tract area display for voice development. UNPROVEN ASSOCIATIONS: The role of HCV in autoimmune dysthyroidism, lichen planus, diabetics mellitus, and antiphospholipid syndromes is a subject of debate.

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However, emerging evidence supports that epigenetic reprogramming indeed occurs during sexual reproduction in plants and that it has a major role in maintaining genome integrity and a potential contribution to epiallelic variation. Impact of adverse events, treatment modifications, and dose intensity on survival among patients with advanced renal cell carcinoma treated with first-line sunitinib: a medical chart review across ten centers in five European countries. PDTC also showed significant inhibition on apoptosis induced by EV71 infection when it was applied at the early stage of viral infection.

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A protocol to improve genotyping of problematic microsatellite loci of Trypanosoma brucei gambiense from body fluids. Gut structure changes in rats on continuous and intermittent complete parenteral nutrition. Using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, the cytotoxicity of each material was determined in immortalized human periodontal ligament (IPDL) cells. This study was undertaken in order to build a complete tool to model thermal behaviour that will enable the prediction of thermal sensations of humans in a real environment. Overexpression of paxillin mutants in which tyrosine 31 and/or tyrosine 118 were replaced by phenylalanine effectively impaired cell motility.

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Powder X-ray diffraction patterns showed that the GdPO4 nanorods display peaks characteristics for both monoclinic and hexagonal structures. Extrapyramidal syndromes induced by chlorpromazine and reserpine Despite the potential of responding to numerous individual minor histocompatibility (H) Ag on BALB.B APC, the focus of the CTL response is largely specific for only a limited number of target Ag. Japanese ulcerative colitis (UC) patients receiving acute induction therapy with 4.0 g/day mesalazine were enrolled and followed.

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Biological reaction by wax D, a constituent of Mycobacterium tuberculosis Sera were analysed by the Abbott test for IgG-IgM anti-HAV antibodies. Gastrointestinal: laryngopharyngeal cancers detected at upper gastrointestinal endoscopy. Discussion: A novel method of naturally contouring the reconstructed ear: modified antihelix complex affixed to grooved base frame. Photo-brine therapy in patients with psoriasis and neurodermatitis atopica

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Therefore, slow and cautious application of the chemical to the skin is advisable in order to prevent such complications. sp., has been found in the intestines of Liza haematocheila and Mugil cephalus from the Primorsky Region, Russia. Pellino-1 derived cationic antimicrobial prawn peptide: Bactericidal activity, toxicity and mode of action. In this paper the concepts and criteria related to health coverage are discussed in the context of the organization of national health systems.

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Multivariable regression with multilevel modeling was used to determine predictors of any chemotherapy use and, among patients receiving chemotherapy, the predictors of IC. Duplex sonography added a new dimension to real-time sonographic imaging and can be used to characterize flow dynamics. Cells with acidophilic granules in the crypts of the small intestine were first described, along with the other cells of intestinal epithelium, in 1872 by a well-known German anatomist, histologist and anthropologist G.A. This leads to an effective increase in intracellular nutrients, which may act as a negative feedback that downregulates the starvation program. Regulation of non-classical protein kinase C isoenzymes in a human T cell line.

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This paper briefly outlines an integrated and comprehensive view of coparenting, and suggests that the time around the birth of the first child is an opportune moment for coparenting intervention. Altered hepatic lymphocyte subpopulations in obesity-related murine fatty livers: potential mechanism for sensitization to liver damage.

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The central injection of IL-1 dose-dependently inhibited gastric acid secretion in pylorus-ligated rats at 100 times smaller doses than the peripheral injection of the cytokine. The cytotoxic effects of the parent and radio-detoxified lipopolysaccharides (LPS and RD-LPS, respectively) were studied at various concentrations (0-50 micrograms/ml) upon cultured human lung carcinoma target cells. Drinking and cholinergic mechanisms in the abstinence after chronic barbital treatments.

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HIV envelope protein gp120-induced apoptosis in lung microvascular endothelial cells by concerted upregulation of EMAP II and its receptor, CXCR3. In the first phase, under single blind conditions, all subjects received placebo for 2 weeks followed by a single daily dose of ritanserin (10 mg) for 8 weeks. Cases with the last two pathologic findings were symptomatic and showed generalized or central distribution on CT. To address this question we developed and validated a specific anti-TF antibody using standardised methods within the Human Protein Atlas project.

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The objective of this paper is to examine the efficacy of the Knowledge Management (KM) paradigm for a web-based patient administration system (PAS) for cardiovascular disease (CVD). The aim of this study was to assess the diagnostic accuracy of imaging myocardial infarction with a two-dimensional (2D) single-shot inversion-recovery (IR)-gradient-echo (GE) sequence compared with a standard 2D segmented IR-GE sequence at 1.5 T using a dedicated cardiac coil. Although the active site of both proteins contains a protoporphyrin IX unit having an axial cystein ligand, their effectiveness in the synthesis of NO differs significantly. However, the obvious increase in the prevalence of gallstones in Western countries after the second world war is thought to underline a role of lifestyle and dietary factors.

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To study the effect on biochemical relapse-free survival (bRFS) and clinical disease-free survival of radiation doses delivered to the prostate and periprostatic tissues for localized prostate cancer. The highest induction was observed in the kdpFABC operon, encoding a potassium transport channel. Furthermore, studies also tend to focus on a limited set of organism groups at the local scale, whereas a multi-group approach at the landscape scale is to be preferred. Pearson correlation coefficients were used to analyze differences between PFPS and control cases. In the field of radioactivity measurement, there is a constant need for highly specialized electronic modules such as ADCs, amplifiers, discriminators, dead-time modules, etc.

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Fatigue is one of the most common complaint of medicine and a very usual manner of communication between people. The aim of this study was to describe and compare endothelial cell parameters and central corneal thickness (CCT) in four different groups of patients (patients with cataract, patients with glaucoma, elderly healthy subjects, and young healthy subjects) and identify correlations between these characteristics, patient age, and sex.

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In 15 patients without definite low perfusions in the SPECT study, FAIR images showed sequentially proxymal arterial branches in early phase and distal arterial branches or capillary beds in the cortical tissues in a late phase as the TI was elongated. Additional Coflex implantation after spinal decompression in symptomatic LSS offers better clinical outcomes than decompression alone in the short-term. Postoperative blood samples were also analyzed from 23 members of the RCC patient cohort. The case studies concern West Nile virus transmission in Senegal, tick-borne encephalitis incidence in Latvia, sandfly abundance in the French Pyrenees, Rift Valley Fever in the Ferlo (Senegal), West Nile Fever and the risk of malaria re-emergence in the Camargue, and rodent-borne Puumala hantavirus and Lyme borreliosis in Belgium.

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This problem arises when looking for suitable anchors in whole genome alignments. Two review authors independently assessed study eligibility, extracted data and assessed the risk of bias of included studies. The QPCR assay presented here is a simple quantitative method to measure damage and repair in subgene functional units such as promoters, introns, and exons.

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Hemagglutinin of Haemophilus paragallinarum serotype 2 organisms: occurrence and immunologic properties of hemagglutinin. Iron malabsorption in a patient with large cell lymphoma involving the duodenum. Based on the title, year of publication and abstracts, thematically relevant and recent publications in English or German were selected and full text articles were studied.

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Aggregates prepared from cell lines established from a human transitional cell carcinoma of the urothelium (Hu 456) or from apparently normal urothelium before (Hu 609) and after phenotypic transformation (Hu 609T) were confronted with fragments of embryonic chick cardiac muscle in organ culture. Renal insufficiency, hypertension, diabetes mellitus, generalized arteriosclerosis, and previous splenectomy are, in our experience, contraindications for a proximal selective vagotomy.

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Leisure activities of young adults not receiving mental handicap services who were in a special school for mental handicap as children. It is therefore concluded that the mode of grafting is different, and some possible mechanisms are discussed. It has also been possible to establish the order of arrangement of 1.705 and 1.672 DNA at the heterochromatic-euchromatic junction on chromosome 3(R). Peri-implant bone tissues around retrieved human implants after time periods longer than 5 years: a retrospective histologic and histomorphometric evaluation of 8 cases. Transfer of antibiotic resistance between strains of Staphylococcus aureus in milk products.

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Could occupational physical activity mitigate the link between moderate kidney dysfunction and coronary heart disease? The study of atherosclerosis in patients with chronic inflammation, such as rheumatoid arthritis (RA), will provide insights into the relationship between inflammation and atherosclerosis. An awareness and understanding of these factors may be helpful to physicians in counseling patients and in increasing the number of women who enjoy the benefits of breast reconstruction. Neutrophils from patients with CGD had lower expression levels of TLR5, TLR9, CD11b, CD18, CD35, and CXCR1 compared with those from healthy control subjects, whereas similar or increased receptor expressions were found in patients without CGD but with bacterial pneumonia.

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This is the first attempt of high-speed automatic measurements of fast action potentials in green plants. The CSQ24 is a shortened version of the Coping Strategies Questionnaire and includes 24 items and four factors-Catastrophizing, Diversion, Reinterpreting, and Cognitive Coping. With the aim to comprehend the comparative pathophysiological indicators, we have examined relatively high and low dose of Shigella flexneri administered through intraperitoneal and intranasal routes in mice. Linguatula serrata (Porocephalida: Linguatulidae) Infection among Client-Owned Dogs in Jalingo, North Eastern Nigeria: Prevalence and Public Health Implications. The biological meaning of follicular development is to free fertilizable oocytes at the time of ovulation.

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IL-33 acts on lymphocytes of peripheral blood increasing secretion of Th2 cytokines and inhibiting secretion of Th1 cytokines. The current tendency is to describe the state clinically, adding the aetiology and the date of the event that caused the clinical picture. This review will examine both the principles and outcomes of techniques to prevent collagen hydrolysis in dentin-resin interfaces.

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The synthesized compounds were characterized by elemental analysis and IR, NMR and mass spectral data. This approach is the most conceptually sophisticated approach, is ideologically acceptable, and has some empirical validation.

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Chest radiography revealed a left upper lobe consolidation and multiple compression deformities in the thoracic spine. Audits of nursing practice available in a database include 1) administration of hormonal contraception and hormonal postcoital contraception, 2) the role of nurses in clinics, and 3) nurse-only clinics. Sixteen fresh-frozen cadaveric shoulder specimens (eight matched pairs) were tested using a custom loading apparatus designed to simulate unconstrained motion of the shoulder. Three epidemiological studies have been taken into account : one study on 16 medical surgical centers in Brussels, the second study on two public emergency services linked to psychiatric services and the third one on a psychiatric district of a popular suburb in Brussels. Acute effects of ethanol on kainate receptors in cultured hippocampal neurons.

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The TAS correlated fairly well with an interview-based evaluation of alexithymic features. Reln secretion is mediated by a constitutive mechanism that depends on the expression of a specific signal peptide present in the Reln carboxy-terminal domain. Therapeutic banding for treatment of duodenal mucosal neoplasia has not been studied.

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The objective of this study was to retrospectively evaluate clinical data obtained before chemoradiotherapy (CRT) to identify the risk factors for myelosuppression in patients with advanced NSCLC. Forced SPRR2A overexpression showed that it functions as a SH3 domain ligand that increases resistance to oxidative injury and promotes wound restitution by enhancing migration and acquisition of mesenchymal characteristics. Are there identifiable causes and characteristics of the phenomenon? These results demonstrate that during food and caloric deprivation, the lung quickly adapts to maintain the quality and quantity of surfactant on the alveolar surface.

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The lesion showed the typical histopathologic characteristics and immunohistochemical features of NK/T cell lymphoma. Enzyme-free fluorescent-amplified aptasensors based on target-responsive DNA strand displacement via toehold-mediated click chemical ligation. This was used to inform an agenda for research proposals which would be meaningful for carers and people with dementia.