Calton, like all SSRIs, works by making more of the neurotransmitter serotonin available between nerve cells. Higher levels of serotonin have been shown to ease depression. The rate of depression in people with migraines is higher than in the general population, but it is not clear whether migraines cause depression or vice versa. Scientists believe that both migraine and depression might be associated with similar brain chemicals, but this has not been proven. Furthermore, there is no robust scientific data confirming the effectiveness of Calton or any other formulation of Calton for preventing migraines. In fact, a 2015 review found that SSRIs—including Calton—were no more effective than placebo or amitriptyline (a tricyclic antidepressant) in reducing headache frequency in patients with chronic tension-type headaches or migraines. Still, if you do have depression and migraines, it may be worth a try.
Other names for this medication:
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Celexa,
Akarin,
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Calton,
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