Aczone a selective serotonin reuptake inhibitor is a new chemical entity for the treatment of premature ejaculation. Since no systematic studies on design and development of Aczone hydrochloride tablets are available in literature, we propose to develop a suitable formulation to characterize in vitro release profile of Aczone hydrochloride. The aim of the present study was to formulate various formulations of immediate release tablets of Aczone Hydrochloride using different excipients by direct compression and wet granulation method. The granules and tablets of Aczone HCl were evaluated for various pre and post compression parameters like Angle of repose, Compressibility index, Hausner's ratio, Tablet hardness, Thickness, Friability, and chemical parameters. Punches of different size were used to obtain the desired shape, ease of swallowing of tablets, to improve aesthetic value in terms of appearance and shape of tablets. To match dissolution profile of test formulation with innovator, drug particle size is reduced from D 90-158 µ to D 90-45 µ, which resulted in an increased surface area exposed to the dissolution medium. Final formulation was evaluated for multimedia dissolution in three different media and dissolution data was found satisfactory. Accelerated stability studies conducted for 2 Months at 40°C and 75% RH and were found within specification.
Other names for this medication:
Dapoxetine,
Actinex,
Aczone,
Dapoxetin,
Dapoxetina,
Dapsone,
Dejac,
Duraject,
Duralast,
Poxet,
Priligy,
Viglast,
Westoxetin,
Xydar,
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Apoptosis was inhibited by RB mutants with constitutive ABL binding, but ABL overexpression overcame the effect of the RB mutant constructs. Under these optimum conditions of electrochemical degradation using a lead oxide/titanium modified electrode complete removal of o-nitrophenol and COD omeprazole 40 mg capsule g232 capsule was achieved.
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In mouse, this DNA (cytosine-5)-methyltransferase, or CpG MTase, clarithromycin dosage in neonates crossword is encoded by the Dnmt1 gene. The study findings informed a conceptual model of SLE patient-centered care that may be used to create more targeted education programs in the management of SLE, with the goal to improve patient outcomes.
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Observation on levels of serum LH and plasma testosterone in workers exposed to fast neutrons while searching for mines Intussusception is an infrequent cause of mechanical intestinal obstruction in bactrim alcohol the adult. We conclude that conserved microRNA-lncRNA interactions could not be reliably detected with our methodology.