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Zyllt (Clopidogrel)
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Clopidogrel

Zyllt bisulfate (Zyllt) is an anti-platelet drug, that is, a drug that inhibits the ability of platelets to clump together as part of a blood clot. Zyllt prevents blood clots by irreversibly binding to the P2Y12 receptor on platelets, preventing adenosine diphosphate (ADP) from activating platelets. It belongs to a class of drugs called P2Y12 inhibitors. Other drugs in this class include ticagrelor (Brilinta) and prasugrel (Effient). Zyllt is similar to ticlopidine (Ticlid) in chemical structure and in the way it works. Unlike ticlopidine, Zyllt bisulfate does not cause serious reductions of white cells in the blood and, therefore, routine blood testing to determine if the white blood cell count is low is not necessary during treatment. The risk of heart attacks and strokes (which usually are caused by blood clots) is increased in patients with a recent history of stroke or heart attack, and patients with peripheral vascular disease. (Peripheral vascular disease is the same as atherosclerotic arterial disease or "hardening" of the arteries in which the arteries become narrowed. It frequently occurs in the legs and often causes claudication or pain in the legs upon walking.) Zyllt bisulfate is used to reduce the risk of heart attacks and strokes in these patients. Zyllt bisulfate was approved by the FDA in 1997.

Other names for this medication:
Clopidogrel, Plavix, Anclog, Anlet, Antiplar, Artevil, Clavix, Clopicard, Clopilet, Clopivas, Deplatt, Diloxol, Duoplavin, Expansia, Farcet, Globel, Grepid, Iscover, Karum, Klopidogrel, Nabratin, Narutis, Nefazan, Noklot, Pidocar, Pidogrel, Pladex, Plagerine, Planor, Tisten, Troken, Trombex, Vaclo, Zyllt,

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Although young people find school nurses approachable and caring, too few access their services. Reciprocally, we studied the effects of chronic intermittent motor cortex stimulation on the capacity for subsequent acute dopaminergic treatments to induce early-gene activation in the striatum. Outcomes after tongue-lip adhesion or mandibular distraction osteogenesis in infants with Pierre Robin sequence and severe airway obstruction. Bis(7)-tacrine, a novel acetylcholinesterase inhibitor, reverses AF64A-induced deficits in navigational memory in rats. Immunoprecipitates of enzymatically iodinated, detergent-solubilized brain particulate protein gave a single band on polyacrylamide gels of apparent molecular weight 95,000--105,000 daltons.

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The aim of the study was to analyze the cases of retrobulbar neuritis and their connection with multiple sclerosis. The aim of this article is to present the determination and the delineation of target volumes for oral cavity and oropharyngeal carcinomas treated with intensity-modulated irradiation.

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A screw is inserted across the proximal aspect of the osteotomy, then the osteotomy is extended across the plantar surface distally. These findings provide evidence that the induction of drug-metabolizing enzymes by 1,2,4-TCB is not due to the action of 1,2,4-TCB itself but is due to its methylsulfonyl metabolite, 2,3,5-TCPSO2Me. Changes in autumn vegetation dormancy onset date and the climate controls across temperate ecosystems in China from 1982 to 2010. The present study investigated the influence of SNARE related genes and their interaction on ADHD susceptibility and their cognitive functions. As a rare neoplasm, only four cases of cystadenocarcinoma of submandibular glands have been previously reported.

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One of them seems to be responsible for inducing neuroleptic-like catalepsy, and the other one for the hyperactivity and blockade of spiperone-catalepsy. An investigation of biological response induced by intermittent noise (trapezoidal noise).

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De novo sequencing of sunflower genome for SNP discovery using RAD (Restriction site Associated DNA) approach. For example, cutaneous marginal zone B-cell lymphomas (formerly designated cutaneous immunocytomas) mirror the features of MALT lymphomas in other anatomic sites. This human Notch homolog, designated NOTCH3, showed both the intracellular portion present in the mouse int-3 sequence and the extracellular portion absent in the int-3.

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Stoichiometry of the Cre recombinase bound to the lox recombining site. Systemic lupus erythematosus: two patients treated with danazol. These results indicate that ERK1/2 is involved in ascorbic acid-induced osteoblastic differentiation during PDL cell attachment to type I collagen. The anodic behaviour of Ni-Cr dental alloys used as porcelain substrates has been investigated in both as-cast and thermal treated conditions. Here we aim to review the epidemiologic evidence related to the association of cigarette smoking, alcohol consumption and the risk of developing SLE.

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Children under 5 years of age or immuno-compromised children of any age who have the highest risk of developing infection and disease when exposed are the main focus for preventive therapy in high burden settings. Use of monoclonal antibodies for blood grouping has made use of new technology, whilst allowing scarce human plasma to be used more appropriately for therapeutic purposes. There are also extensive secondary interactions which provide an additional buried area and contribute significantly to the strength and specificity of recognition. For all 3 proteins the molecular architecture is made up of an antiparallel 3-helix bundle.

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Multiple myeloma: optimal use of salmon calcitonin in the management of myeloma osteoclastic bone disease. In this study, we investigated all seven MCPH loci in patients with primary microcephaly from 112 Consanguineous Iranian families. Infection-related mortality is more common in kidney allograft recipients with pre-existing diabetes mellitus.

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Blood was drawn for culture and coagulation profiles, and patients underwent pulmonary function tests, esophageal manometry, and intraesophageal pH monitoring before and after treatment. It is a universal bar: the superior and inferior borders are identical. Concordance in the radiological diagnosis of thoracolumbar spine fractures. We propose that the role of cis-interactions and their signaling on fine-grained patterning and cell fate decisions is dependent on whether they drive cis-inhibition or cis-activation, which could be controlled during development.

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Our goal is to investigate how recent low-cost devices can be used in real-life settings for the prevention of CVD, and whether using these devices has an advantage over subjective self-assessment. This response was not reproducible in vitro, since it was mediated by the release of sensory neurotransmitters in a capsaicin-like action. It is suggested that there is a difference in differentiation between acute and chronic leukemic cells.

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Further, phosphorylation of Chk1 at ATR sites reduces the interaction between Chk1 and the MCM complex, facilitating chromatin release of phosphorylated Chk1, a critical step in the initiation and amplification of cell cycle checkpoint. Changes in liver calcium content in relation to serum triiodothyronine (T3), thyroxine (T4) and T3/T4 ratio in rats treated with CCL4. Since the native wheat germ agglutinin is a strong activator of platelets and the succinylated derivative was devoid of all activity, it appears that a sialoprotein acts as the biologic receptor of wheat germ agglutinin in human platelets.

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The role of complement regulatory proteins (CD55 and CD59) in the pathogenesis of autoimmune hemocytopenias. These cells had a diffuse appearance and their basal laminae were discontinuous or absent. Antibiofilm effects of endodontic sealers containing quaternary ammonium polyethylenimine nanoparticles. Specific immunohistochemical identification of Candida albicans in paraffin-embedded tissue with a new monoclonal antibody (1B12).

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Experience in the eradication of enzootic plague in the north-west part of the Caspian region of the USSR. The 25S and 1,25S lactones were more potent than the 25R and 1,25R isomers. Biodegradable polydioxanone stent as a new treatment strategy for tracheal stenosis in a rabbit model. A5 and B2 through a set of specific primers using the PCR technique. A subcutaneous long-acting gonadotropin-releasing hormone agonist (GnRH agonist) injection was given on a monthly basis resulting in a substantial improvement in his aggressive behaviour and renewed socialisation.

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Inhibition of phosphorylation of synapsin I and other synaptosomal proteins by beta-bungarotoxin, a phospholipase A2 neurotoxin. By application to several highly symmetric molecules, SEAS-CASCI is demonstrated to reduce the propensity for unphysical spatial symmetry breaking and eliminate resulting errors in the potential energy surfaces and molecular properties relative to the SA-CASSCF description. The 2-dimensional gel electrophoresis (2-DE) and matrix-assisted laser desorption/ionization time of flight tandem mass spectrometry (MALDI-TOF-MS/MS) were used to screen and identify the differentially expressed serum proteins among all subjects. This study aimed to quantify volumetric and positional variations of the target volume during IMRT.

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A robust association test for detecting genetic variants with heterogeneous effects. The self-perception of infertility is common among sexually active urban female adolescents and may pose another barrier to contraceptive use. To determine the mental health status, including depression and quality of life among members of the Thammasat hospital elderly club which covers elderly members in northen Bangkok, Pathumthani and Ayutthaya province. The involvement of the facial bones by fibrous dysplasia is an uncommon event, which causes different syndromes according to the extent of bone invasion.

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A simple method for assaying contact toxicities of insecticides, with results of tests of some organic compounds against Calandra granaria L. We report three infants with an initial diagnosis of developmental delays, recovery of normal development following intervention in a multidisciplinary center, and subsequent regression into classic autism following their discharge from the program. Several effects of prolactin have been characterized in various tissues of the gastrointestinal tract. Comparison of the effects of enteral psyllium, magnesium sulphate and their combination for removal of sand from the large colon of horses.

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Organized trauma systems and trauma centers are thought to improve trauma outcomes. Volumes estimated using cubic planimetry are more accurate than step-section planimetry, and require fewer cross-sections, even for complex objects.

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