Sulfametoxazol is a combination product consisting of sulfamethoxazole and trimethoprim. Sulfametoxazol DS (double strength) tablets contain 800 mg of sulfamethoxazole and 160 mg of trimethoprim. Sulfametoxazol is rapidly absorbed after oral administration and peak blood levels occur 1 to 4 hours after oral administration. Sulfamethoxazole has a mean serum half life of 10 hours. Trimethoprim has a mean serum half life of 8 to 10 hours. Sulfametoxazol's components - sulfamethoxazole and trimethoprim - are primarily excreted by the kidneys. The medication is distributed to the sputum, middle ear fluid and vaginal fluid. Sulfamethoxazole inhibits the synthesis of dihydrofolic acid by bacteria. Trimethoprim reversibly inhibits an enzyme known as dihydrofolate reductase and reduces the production of tetrahydrofolic acid. Sulfamethoxazole is a white, odorless, tasteless compound. Trimethoprim is a white to light yellow, odorless and bitter compound.
Other names for this medication:
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Actrim,
Astrim,
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Bactelan,
Bacterol,
Bacticel,
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Bactoprim,
Bactricid,
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Bactropin,
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Biotrim,
Biseptol,
Bitrim,
Ciplin,
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Septra,
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Soltrim,
Spectrem,
Suftrex,
Sulfa,
Sulfamethoxazole,
Sulfametoxazol,
Sulfatrim,
Sulotrim,
Sulprim,
Sumetrolim,
Suprim,
Sutrim,
Tagremin,
Theraprim,
Tmps,
Trifen,
Trimesulf,
Trimesulfin,
Trimexazol,
Trimezol,
Trimol,
Trimoxsul,
Trisul,
Trizole,
Urisept,
Vanadyl,
Wiatrim,
Xepaprim,
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