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Unmasking a functional allosteric domain in an allosterically nonresponsive carbamoyl-phosphate synthetase. Regional perfusion with either intra-arterial doxorubicin hydrochloride or cisplatin combined with limb salvage surgery and postoperative radiation are highly effective in preventing local recurrences and preserving functional extremities in patients with soft-tissue sarcoma. Complete Genome Sequence of Streptomyces clavuligerus F613-1, an Industrial Producer of Clavulanic Acid. Results indicate a clear role for notions about lactation and the proper timing of appropriate foods in growth retardation of young children.

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The antimicrobial activities of KY-087 against Gram-negative organisms, such as Enterobacter sp., Serratia, and Pseudomonas sp., were less active. Pulpotomy therapy for the primary dentition has developed along three lines: devitalization, preservation, and regeneration. Low recruitment represents the main cause of early termination of cardiovascular clinical trials.

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Although the results help to improve understanding of the role of fear-avoidance beliefs, further studies are needed to fully understand the influence of psychological and clinical factors on the development of disability in patients with subacromial shoulder pain. Prochlorperazine and transdermal scopolamine added to a metoclopramide antiemetic regimen. Although a predominantly cavitary pattern appears to be more common with M xenopi, the majority of patients with M xenopi had CT patterns of random nodules or consolidation and/or ground-glass opacities rather than classically described findings. Stage can inform interventions to ameliorate disability and thus reduce the risk of a subsequent hospitalization in this population. 3D alternating direction TV-based cone-beam CT reconstruction with efficient GPU implementation.

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Influence of aging on leg muscle reflex responses to stance perturbation. There is no doubt that hypertension is of importance to the health of the elderly, in terms of both mortality and disability. Cells brainwashed by FOXM1: do they have potential as biomarkers of cancer?

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The appearance of the presumed Renshaw cells was also compared with that of a larger sample of neurons from the ventral part of lamina VII which was studied light microscopically in semithin sections. Difference in motility between anterior and posterior gastric wall after anterior and/or posterior truncal vagotomy The Institute of Hematology and Blood Transfusion in Sofia and the Bulgarian Transfusion Service Comparative analysis of all models showed that the maximum stress overall was in the cervical portion of the secondary abutment.

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The developed compounds showed PqsD inhibition with IC50 values in the single-digit micromolar range. Microviridins were produced either directly from fosmid clones or after insertion of environmental DNA-derived gene cassettes into a minimal expression platform in Escherichia coli. Mass spectrometry quantification of PICALM and AP180 in human frontal cortex and neural retina. Asynchronous glands in secretory pattern endometrium: clinical associations and immunohistological changes.

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It can be concluded that the intense investigations of the methanol fraction obtained from Trapa natans root extract can be done to provide an alternative natural therapy for hyperglycemia. The two analogs employed: 1,25 (OH)2-22 (E)-dehydro-24-monohomo vitamin D3 (Compound A) and 1,25 (OH)2 -22 (E)-dehydro-24 dihomo-vitamin D3 (Compound B) may be useful in the therapy of pathologic proliferative disorders including psoriasis, particularly since they are less toxic and have less effect on calcium metabolism than vitamin D3.

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Hyperferritinemia increases the risk of hyperuricemia in HFE-hereditary hemochromatosis. The individualized neuromuscular quality of life questionnaire: cultural translation and psychometric validation for the Dutch population. C3a activates the respiratory burst in human polymorphonuclear neutrophilic leukocytes via pertussis toxin-sensitive G-proteins. Modal shift towards public transport could help slow down, or even reverse, this trend. Between 2008 and 2012, 145 patients underwent resection of anterior mediastinal mass.

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Nationwide Birth Weight and Gestational Age-specific Neonatal Mortality Rate in Taiwan. The results are surprising and indicate that the gene is a partial reverse-transcribed pseudogene that has been inserted into the genome at 12q by chance and has not resulted from the prior tetraploidization of the human genome.

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The epidemiology of sudden infant death syndrome and attacks of lifelessness in Sweden. It has been suggested that ungulate males tend to have more frequent and longer aggressive interactions with rivals of similar age or social status than with males of dissimilar status.

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In the setting of pediatric gastroenterology, the importance of FC has increased over time. This incubation results in no hydrolysis or loss of other resistant oligosaccharides such as FOS, GOS, XOS, resistant maltodextrins (e.g., Fibersol 2) or polydextrose. Finally, an analysis of the data was completed based on a life-world hermeneutic approach.

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Clinical hepatic support by on-line plasma treatment with multiple sorbents - evaluation of system performance. Amrinone and dobutamine as primary treatment of low cardiac output syndrome following coronary artery surgery: a comparison of their effects on hemodynamics and outcome. Chitooligosaccharides could effectively accelerate the proliferation of pancreatic islet cells. In control ligaments, fibroblasts were shown by immunofluorescence microscopy to contain actin, vimentin, and myosin in their cytoplasm. The actin filaments show a right-handed twist and are connected by a structure that links adjacent filaments with the same polarity at the same axial level, then runs parallel to the filaments, and finally forms a link between two actin filaments whose polarity is opposite to that of the first pair.

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To date, it remains unknown if spatial and temporal filtering of nociceptive information is supported by similar analgesic mechanisms. GFAP and Vimentin were chosen as glialtypic markers for neurotoxicity. Two review authors independently extracted data and assessed risk of bias of included studies. We have studied the changes of PKC activity in an animal model of impaired cognitive functions as a consequence of an exposure during embryonic life to an antimitotic agent, methylazoxy-methanol acetate (MAM). In conclusion, Med13p maintains mitochondrial structure, function, and normal oxidative stress sensitivity through cyclin C nuclear retention.

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There is significant interest in the generation of improved assays to clearly identify experimental mice possessing functional vision, a property that could qualify mice for inclusion in behavioral and neuroscience studies. Currently, CFI comes in three forms: synchronous signal processing, asynchronous signal processing, and time domain analysis. A brief summary of the indications for and methods of induction of labour. Whether the decrease of PID cases represent a true decrease or not is not known. Exposure to maternal HIV impacts infant respiratory health through an increase in known risk factors such as increased preterm birth and low birth weight, suboptimal breastfeeding, increased psychosocial stressors and increased exposure to infective pathogens.

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The putative catalytic site of restrictocin includes Tyr47, His49, Glu95, Arg120 and His136. Cardioprotective effects of ischaemic preconditioning are not mediated by prostanoids. We considered the two compositions Ge(1)Sb(1)Te(1) and Ge(2)Sb(4)Te(5). We describe a case identified by ultrafast computed tomography (CT) and we review the literature regarding this entity. Present-day problems associated with this food source still involve some wastewaterborne bacterial illnesses.

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Threonine, tryptophan and histidine requirements of immature beagle dogs. A 31 year old woman presented with a chest wall abscess due to Actinomyces israellii and Porphyromonas asaccharolytica (previously Bacteroides asaccharolyticus). Phosphorylation is a key process regulating a large number of fundamental biochemical reactions in living organisms. Therapeutic impact of follistatin-like 1 on myocardial ischemic injury in preclinical models. Our findings in these cases suggest that eosinophilic pustular folliculitis may vary in clinical appearance.

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Here, we demonstrate using mice brain slices that activation of T-channels in thalamocortical neurons maintained in the depolarized/wake-like state is critical for the reliable expression of tonic firing, securing their excitability over changes in membrane potential that occur in the depolarized state. Severe allergic reaction during thiopental sodium anesthesia: report of case. These results show that multiplexed real-time detection and analysis, great flexibility, and portability make the combination of these technologies an ideal platform for easy and fast use in any laboratory.

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Such effects make the heat conduction obey a Fourier-like law in a wide range of lattice lengths. The study population consisted of 393 male patients aged 40 to 70 years, who were admitted to the urology clinics of four different institutions from February to March 2005. The involvement of specific cell surface receptors and signal transduction pathways in mediating the effects of fHAs was tested using small interfering RNA (siRNA) approaches and kinase inhibition assays. The impairment did not extend to the familiar, previously established associations. Phospholipase D-dependent and -independent mechanisms are involved in milk protein secretion in rabbit mammary epithelial cells.

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In contrast, the NQO1 protein levels and enzyme activity were lowest in rat-kidney cytosol, whereas the highest amounts of NQO1 protein and activity were found in lung cytosols, followed by those of liver. More detailed cost distribution analysis was then conducted for a group of general surgical amputees corroborating data from the resource utilisation system, Otago surgical audit and patient records. In food industry, LAB are often exposed to metal ions induced stress. Nitrifying and denitrifying bacteria as well as phosphate-accumulation bacteria were more abundant in municipal WWTPs, while sulfate-reducing bacteria were almost only detected in textile WWTPs.

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Abstract Overexpression of ATP-binding cassette (ABC) transporters in cancer cells results in multidrug resistance (MDR) which leads to unsuccessful chemotherapy. Reasons for initiating and weaning breast feeding, the formal and informal supportive resources of participants during breast feeding were collated at the third time points.

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The ocular findings are compared and contrasted with embolic lesions due to Candida albicans. We report successful surgical repair of middle lobar torsion after upper lobectomy. The aim of this study was to examine the potential role of the spinal PKA/CREB signaling pathway in the development of bone cancer pain. Variables which predict burnout experienced by oncology clinical nurse specialists. Histochemical fiber types and fiber sizes in human masticatory muscles.

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The use of vital statistics data to study causes of death in Latin America is examined. A prospective study was undertaken to quantitatively evaluate the amount of gray scale enhancement of ultrasound images of six canine livers, spleens, and left kidneys that occurs after intravenous injection of Imagent. Such changes are not likely related to sex, clinical symptoms or duration of untreated psychosis, but are influenced by age. Expression of human acylphosphatase in Escherichia coli affects intracellular calcium levels. The role of sanitary-and-selection committees in the system of serviceman prophylactic medical examination

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Chemical imaging and solid state analysis at compact surfaces using UV imaging. The root of this problem is the low frequency of events in the majority of surgical clinical research. The other three smaller CNVs (sized from 36.1 to 76.4 Kb) on chromosomes 2, 15 and 32 in clone-3 and clone-6 were verified by at least one of the three validations. SUMMARY and recommendations of report on planned parenthood clinics by the Committee on Public Health Relations of the New York Academy of Medicine. The complete amino acid sequence of rat testes metalloendopeptidase (EC 3.4.24.15) was deduced from the nucleotide sequence of a cDNA clone isolated by screening a rat testes library with a polyclonal antibody raised against a homogeneous preparation of the rat testes enzyme.

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The molecular program controlling hematopoietic differentiation is not fully understood. Bupivacaine placental transfer characteristics suggest passive diffusion rather than active drug transport and appear to be influenced by the maternal and fetal plasma protein binding, fetal pH, and placental uptake. Intraoperative brain activity monitoring and postanesthesia care unit length of stay: results of a systematic review. This is accompanied by a time- and dose-dependent lysosomal destabilization--as evaluated by a decreased lysosomal uptake of the metachromatic fluorochrome, and weak base, acridine orange--in combination with leakage to the cytosol of lysosomal contents, including hydrolytic enzymes.

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The results also suggest that the inverse relationship between the increase of heme oxygenase activity and the decrease of cytochrome P-450 content would be a biochemical phenomenon seen in regenerating liver and that the phenomenon would not be simply due to the surgical stress to the animals. The initial rate of horseradish peroxidase (HRP)-catalysed chemiluminescence (CL) reaction in an aqueous compartment of liposomes was applied to the estimation of membrane permeability of liposomes.

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The Cancer Communication Assessment Tool for Patient and Families (CCAT-PF) is a unique tool developed to measure congruence in patient-family caregiver communication employing a dyadic approach. National survey on the susceptibility of Bacteroides fragilis group: report and analysis of trends in the United States from 1997 to 2004.

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Using the estimated equilibrium constant, and the concentrations of creatine, creatine phosphate, and adenosinetriphosphate found, a value for the concentration of free adenosinediphosphate is obtained which is considerably less than that found by direct chemical analysis. Birth of common shovelnose rays (Glaucostegus typus) under captive conditions. The authors compared the responses of patients with atopic asthma to two cromolyn drugs of different generations, tailed and intal.

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Seeing is believing: new updates on coronary microvascular dysfunction. The recently marketed Advanta V12 large-diameter-covered stent is pre-mounted and requires 9 (8)-11 Fr delivery systems. New links between SOD1 and metabolic dysfunction from a yeast model of amyotrophic lateral sclerosis.

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To examine the effect of shoulder position on scapular kinematics across the range of motion (ROM) of a traditional push-up. These findings demonstrate for the first time that very potent antibacterial substances can be produced through a mechanism involving intestinal bacteria and exocrine pancreatic secretions.

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This review article addresses the effects of environmental factors such as pH, temperature, cytokines, hormones, and oxidative stress on periodontal biofilm formation and bacterial virulence. CD28 is required to promote T cell proliferation and cytokine production, while the cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) functions as a negative modulator for T cell activation.

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Effect of molybdenum on nitrogen fixation by Clostridium butyricum. Twelve sources provided data on 1695 cases of birth defects, 1579 of which were suitable for analysis. Based on these results we cannot find any justification for the application of anti-LC1 and anti-SLA tests in the routine laboratory testing of viral hepatitis-related autoantibody serology with the only potential exception being the anti-LC1 screening in anti-LKM1(pos)/HCV(pos) patients.

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Twenty-eight community-dwelling adults with acquired brain injury. Pneumococcal meningitis: epidemiological profile pre- and post-introduction of the pneumococcal 10-valent conjugate vaccine.

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The caspase 8 shRNA-modified and superparamagnetic iron oxide (SPIO)-labeled hMSCs were injected into the border zone of the infarcted region of rat heart. The isolated compounds were screened with two anticancer models. Targeting single-walled carbon nanotubes for the treatment of breast cancer using photothermal therapy. Symptomatic cavernous malformations of the brainstem: functional outcome after microsurgical resection.