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Clones expressing high levels of Bcl-2 were resistant to cisplatin- and etoposide-induced cytotoxicity in a dose-dependent manner. To measure the changes in pulmonary function and thoracic volume associated with surgical correction of kyphotic deformities. Rostrocaudal branching within the climbing fibre projection to forelimb-receiving areas of the cerebellar cortical C1 zone. In the present experiment, autistic, language-impaired, and non-language-impaired children were compared on a dichotic listening task designed to overcome some of the deficiencies of earlier research.

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Identification of a region of the human endothelin ETA receptor required for interaction with bosentan. Transcriptional response to stress in the dynamic chromatin environment of cycling and mitotic cells.

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Use of the proverbs test for differentiating schizophrenics from normals. Angiogenesis is a very complex physiological process, which involves multiple pathways that are dependent on the homeostatic balance between the growth factors (stimulators and inhibitors). Interpretations of results was aided by considering the build up of negative disequilibrium. Pharmacological tests showed a weak antiarrhythmic and hypotensive activity of the screened chiral 2-benzylamino-1-butanols.

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The clathrin adaptor complex AP-2 mediates endocytosis of brassinosteroid insensitive1 in Arabidopsis. Oswestry disability scores and numeric pain ratings were also recorded. canis infection and that the nature and extent of this degeneration is similar, regardless of whether mice had been administered parasites alone or in combination with lead. IGF-I appears to be a good indicator of rhGH effect on bone (Tab. The treatment results were evaluated from lateral cephalometric radiographs.

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Determination of alkaline phosphatase isoenzymes by an original kinetic method in patients with chronic active hepatitis Eight nurses of varying levels of practice who work a variety of shifts participated to explore the clinical handoff process in the emergency department of a pediatric teaching hospital. The type-specificity of immune protection against Shigella paradysenteriae (Flexner).

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A database search was performed in Scopus, PubMed, and ScienceDirect with an additional hand search on December 5, 2013. All cases had situs solitus of the atria and concordant connections between atria and ventricles. The effect of ketamine infusion to control the intractable pain which had not responded to ordinary procedures in 12 patients with advanced cancer were evaluated. Outcome reliability in non-ambulatory boys/men with Duchenne muscular dystrophy.

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At this point it adopts a lower symmetry wrinkled structure that can be described by a spherical harmonic deformation. Strategies aimed at lowering glycemia are based on the understanding of mechanisms regulating glucose metabolism. Results of SAVE and AIRE show a clear survival benefit for the patients. Micelles of SDS cause the labelling also of the beta polypeptide chains, while Triton X-100 micelles have little ability to mediate the labelling of the toxin. Mitochondrial dysfunction has been potentially implicated in both human and experimental hypertension.

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Serum levels of adipocyte fatty acid-binding protein are independently associated with left ventricular mass and myocardial performance index in obstructive sleep apnea syndrome. Further clinical studies, preferably in prospective randomized trials, are required to demonstrate an advantage of this new regimen compared to continuous combined HRT. Dual-echo breathhold T(2)-weighted fast spin echo MR imaging of liver lesions.

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The duration of pre ejection and ventricular ejection did not change significantly with gestational age. Stimuli from these other modalities may distract us from pain and reduce its perceived strength. Under comparable conditions of labeling, human platelets appeared to accumulate almost all the radiolabel within the cytosol. Altered intrathalamic GABAA neurotransmission in a mouse model of a human genetic absence epilepsy syndrome.

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This correlation remained when controlling for general cognitive ability and perceptual speed. The TIMI risk score may serve as an effective risk stratification tool among chest pain patients selected for EDOU placement.

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Cultured primary neurons are a well-established model for the study of neuronal function. Clinicians should be cautious when evaluating radiographs of younger obese persons for the presence of asbestos-related pleural plaque, particularly in populations having an anticipated low or background prevalence of LPT. However, genotypes A and B have occasionally been identified in dogs.

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The following endpoints were considered: endpoint total, high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) and triglycerides. The venom similarly triggers acetylcholine (ACh) release from synaptosomes purified from Torpedo electric organ. Adding zero point energies finally makes the beta phase the ground state of elemental boron by 3 meV/B. The results showed that planting was more important in maintaining the abundance of Korean pine (Pinus koraiensis), a climax keystone species in this region, under the high-intensity harvesting option during early succession.

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We have developed two novel approaches to more precisely characterize seizure-related phenotypes in their native state in prickle mutant flies. The purpose of this study was to examine progression and reversal of microvascular complications when rats were fed a high fat diet. Anti-c-MET Nanobody - a new potential drug in multiple myeloma treatment. The first pathomorphologic changes appeared in the liver, stomach, small intestine, and as the intoxication period was prolonged they appeared in other internal organs and brain. Differential action of penicillin and uv-light on endosymbionts of the ciliate Euplotes crassus.

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The patient is usually physically active on her feet and localizes the pain accurately. High-performance liquid chromatography method with ultraviolet detection for the quantification of the BCR-ABL inhibitor nilotinib (AMN107) in plasma, urine, culture medium and cell preparations. We calculated mean hourly bed occupancy in each ICU and hourly bed occupancy for patients on mechanical ventilators. The length of the skin incision in the experimental group was shortened by 4.8 cm compared to that in the control group. Importance of the cytochemical study of leukocyte enzyme activity in infectious allergic myocarditis

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A retrospective review of 113 women with erosive vulvar lichen planus. The limited success in achieving insulin independence of patients with type 1 diabetes mellitus after islet transplantation from a single donor, mainly due to early loss of transplanted islets, hampers clinical application of islet transplantation.

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The role of the lungs during exercise, the effect of physical training on lung function, and the attributes of lung function that are important for superior athletic performance are discussed. This paper focuses on the preclinical and clinical experience with drug-eluting non-vascular stents with emphasis on drug delivery systems and regulatory requirements for their development.

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As in vivo, axo-somatic, axo-dendrite and axo-spine forms of synaptic endings have been observed. Genetic and electrophysiological analysis of these family members has provided insight into how organisms use mechanosensitive channels for osmotic regulation in response to changing environmental and developmental circumstances. The mean F content of the foods originating from the F-rich water for 3 decades. This discrepancy may be attributable to the fact that only the acetylated intermediates of INH may have a hepatotoxic potential. The patients were evaluated with regard to symptoms, and indications for permanent pacemaker implantation were studied.

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Serum C-X-C motif chemokine 13 is elevated in early and established rheumatoid arthritis and correlates with rheumatoid factor levels. Triticeae members, particularly wheat and barley, make an important contribution to world food reserves by providing rich sources of carbohydrate and protein. How to determine local elastic properties of lipid bilayer membranes from atomic-force-microscope measurements: a theoretical analysis. We have produced bsAbs directed against the membrane expressed idiotype of the murine B cell lymphomas BCLI and 38C13, and murine CD3 complex.

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Ninety-three cases with 31 in each group of chronic superficial gastritis (CSG), chronic atrophic gastritis (CAG), or gastric cancer (GC) were analyzed immunohistochemically for proliferating cell nuclear antigen (PCNA) and Bcl-xl as biomarkers of proliferation and apoptosis, respectively, and CD44, CD166, and LGR5 levels by qRT-PCR as markers of gastric CSCs. Severe autoimmune hemolysis should thus be considered as a cytomegalovirus-associated complication in HIV infection. Ovulation (P plasma levels higher than 2000 pg/ml) was achieved in 3 patients during the first month of NET-EN treatment but luteal function appeared to be insufficient. Typically, inference for the difference in AUC statistics from nested models is derived under asymptotic normality.

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Choroidal folds appeared hypofluorescent in FA and hyperfluorescent in ICGA. In this study, we describe the effects of UDCA on lumbar spine bone mineral densities over a 3-year period during which patients were enrolled in a randomized, double-blind, therapeutic trial of UDCA for the treatment of PBC. To determine whether rabbit synovial fibroblasts can synthesize nitric oxide (NO) and, if so, how production is regulated by cytokines. Prevalence, clinical features and quantification of genital non-viral infections. Atrophied glands of socially deprived males strongly respond to the odor of ethereal extract of gland secretion.

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This novel algorithm which we call MAP-DP (maximum a-posteriori Dirichlet process mixtures), is statistically rigorous as it is based on nonparametric Bayesian Dirichlet process mixture modeling. Here, we present the cloning, heterologous expression, and detailed functional and pharmacological characterization of two honeybee 5-HT2 receptors. An understanding of the pathophysiology, imaging appearance, and demographics of these entities is essential in guiding optimal care. A strong inverse relationship was found between the triangular fibrocartilage complex thickness and the ulnar variance. Repetitive endocardial focal activations in the LV endocardium may be associated with activation of subendocardial PFs.

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Surgical practice of primary care physicians in a rural state: implications for curriculum design. PrEP scale-up depends upon primary care providers and community-based organizations (CBOs) sharing PrEP information. Two controls were matched to each case on age and patterns of Health Plan membership.

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A 42-year-old male was hospitalized in the surgical ward for abdominal pain due to stenosis of the splenic flexure of the colon and abscess around the stenosis. These features included skin reactivity to other inhalant antigens and to molds other than Aspergillus fumigatus (Af) plus clinical manifestations of rhinitis, conjunctivitis, asthma, eczema, urticaria, anaphylaxis, food allergy, and drug allergy. To determine if conservative treatments (manual therapies, physical medicine methods, medication, and patient education) relieved pain or improved function/disability, patient satisfaction, and global perceived effect in adults with acute, subacute, and chronic mechanical neck disorders (MND) by updating 11 systematic reviews of randomized controlled trials (RCT).

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Treatment of static SMC with serum, platelet-derived growth factor, or thrombin stimulated SMC proliferation, whereas exposure of SMC to cyclic stretch blocked the proliferative effect of these growth factors. Absence of withdrawal effects of ritanserin following chronic dosing in healthy volunteers.

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Abdominal aortic aneurysm (AAA) is a life-threatening vascular disease. We also propose some potential pathways that may hold clues regarding the pathogenesis and/or therapy for ARDS.

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Coronal CT sections with thin slices and intravenous contrast enhancement are recommended when empty sella is to be documented by CT. Microalgae and cyanobacteria are promising organisms for sustainable biofuel production, but several challenges remain to make this economically viable, including identification of optimized strains with high biomass productivity.

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Data indicating that pre-transplant abstinence is an associated predictive factor for alcoholic recidivism supports the reasoning behind this. Breath sounds at 6 sites on the chest wall, airflow rate at the mouth, and ECG were digitized and recorded for 30 seconds. Combined anterior chamber washout, amniotic membrane transplantation, and topical use of corticosteroids for severe peripheral ulcerative keratitis. Cytotoxic effect of sensitized lymphocytes on antigen content of target cells

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Treatment included conservative management in one case and in the other cases, surgical removal by intra- or extraoral approaches, the latter being the most common approach carried out. In the present study, we investigated the antifibrotic effect and mechanisms of action of mistletoe extracts in a rat model of carbon tetrachloride (CCl4)-induced hepatotoxicity. The results show a good correlation with some high- and low-responder strains, such as CBA and DBA/2 or A/J and SJL, respectively, but not with C57BL/6, B10.S or B10.A strains. There is no significant difference in average nuclear back scattering between sides. Expression of different conformations of p53 in the blast cells of acute myeloblastic leukaemia is related to in vitro growth characteristics.

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Employing a novel ELISA-based assay for plaque forming cells, long-lived radioresistant IgE- and IgG-secreting cells were identified in differing ratios in lymph nodes, spleen, and bone marrow of both species. Idiopathic chylothorax is a debilitating disease that can lead to respiratory and metabolic compromise and fibrosing pleuritis. There were no significant differences between the two groups for age, sex, duration of illness and type of drug treatment. Transesophageal echocardiographic guidance of transcatheter ventricular septal defect closure.

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Safety of different acupuncture manipulations for posterior circulation ischemia with vertigo. The treatment planning resulted in a favorable dose distribution. The role of other factors like social conditions (immigration, homelessness, working conditions), co-morbidities (silicosis), and characteristics of anti-TB treatment is still controversial.

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Dr Craddock discusses the development of both novel conditioning regimens and post-transplantation strategies aimed at reducing the risk of disease relapse. Published case reports on AIN induced by penicillin and related drugs are reviewed and compared.

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New MALDI matrices based on lithium salts for the analysis of hydrocarbons and wax esters. Euglycemizing effect of partial jejuno-ileal resection in rats treated with streptozotocin Dimorphic microtriches were present on the inner margin of the suckers and around the genital pore, while the only area to contain dimorphic microtriches in the larva was the surface of the rostellum. A robust approach for the analysis of peptides in the low femtomole range by capillary electrophoresis-tandem mass spectrometry.

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To investigate the sedative and hypnotic activity of paeoniflorin and freeze-dried Sini San powder on mice and provide a reliable method for determining the pharmacodynamic material basis of Sini San. A gene (FRE1) was identified which encodes a protein required for both ferric iron reduction and efficient ferric iron assimilation, thus linking these two activities. We reviewed biologically feasible interventions for patients diagnosed as having PML or other infections while receiving natalizumab therapy.