on all orders above $300.00

FREE Pills!


for free with every order



Less than in your
local pharmacy

Search by letter:


Enter coupon: (if you have one)

Filibuvir (Ribavirin)

Filibuvir, also known as tFilibuvir, is an antiviral medication used to treat RSV infection, hepatitis C and some viral hemorrhagic fevers. For hepatitis C, it is used in combination with other medications such as simeprevir, sofosbuvir, peginterferon alfa-2b or peginterferon alfa-2a.

Other names for this medication:
Ribavirin, Rebetol, Copegus, Alfater, Beclabuvir, Boceprevir, Daclatasvir, Daklinza, Dasabuvir, Elbasvir, Filibuvir, Hepcinat, Hepcvir, Incivek, Kipferon, Ledifos, Ledipasvir, Miravirsen, Multiferon, Olysio, Ombitasvir, Paritaprevir, Pegasys, Pegetron, Pegintron, Rebetron, Resof, Setrobuvir, Simeprevir, Sofab, Sofovir, Sovaldi, Sylatron, Technivie, Telaprevir, Veldona, Victrelis, Viroclear, Zepatier,

Similar Products:
Monozeclar, Acitop, Kenazole, Deworm, Epitomax, Coumadin, Sinequan, Inhipump, Fenixa, Naxy, Trioday, Takepron, Resprim, Omizac, Finpecia, Vikrol, Neuril, Moxyvit, Disulfiram, Finax, Elgam, Anxiron, Loxof, Claneksi, Imacillin, Ygielle,

filibuvir pfizer

kanekoi DNA has a major satellite at the same buoyant density in neutral CsCl gradients as satellite III of D. Nervous system diseases among miners of the Extreme North and the problems of their prevention Radiation-induced inactivation of dihydroorotate dehydrogenase in dilute aqueous solution. The intensities of repair labelling measured for the three human cell lines of normal, xeroderma pigmentosum group C (XP-C) and Cockayne syndrome group B (CS-B) are in good agreement with their known repair capabilities. Computation is carried out using the integrated nested Laplace approximation, which is fast.

filibuvir pfizer connection

Upon gentle manipulation of the bowel, an unexpected bleeding diathesis was manifested by the formation of several large haematomas resulting in a large amount of blood loss (approximately 800 ml). Statistical analysis showed that retrieving them was not at random.

filibuvir pfizer animal health

This report describes methods for mapping aging trajectories and intercohort trends, using linear latent-growth models of relatively brief follow-up data (six years in the examples). Magnetoencephalographic observation of cortical spreading depression elicited by experimental focal brain ischemia in rats

filibuvir pfizer viagra

Additionally, closely related aspects like general software procurement criteria, the overall attitude of health IT executives, users, and management towards OSS and its current and future use could as well be assessed. and i.v., suggesting that the virus might be transmitted to the central nervous system (CNS) by the neuronal route rather than by blood stream.

filibuvir pfizer patient

Some indicators for a broad assessment of the magnitude of protein-calorie malnutrition in young children in population groups. In all children successfully operated upon, the ECG signs of right ventricular hypertrophy disappeared. This was observed only during lengthening and it ceased when the lengthening was stopped. A case of brain tumor complicating a full-term pregnancy is reported. Dietary cyclosporine after a period of UV exposures did not affect ensuing UV carcinogenesis.

filibuvir hcv infection

L9 (3(4)) orthogonal design was adopted to optimize the preparation process. Non-invasive brain stimulation (NIBS) is a promising tool for facilitating motor function. These nodules, which are being detected by radiographic techniques in cirrhotic livers and removed during transplantation procedures, represent a new and challenging histologic spectrum of liver pathology. Shared and specific independent component analysis (SSICA) is an exploratory method based on independent component analysis, which performs between-group network comparison.

filibuvir pfizer products

Several Mycoplasma and Acholeplasma species chosen at random and solubilized with sodium dodecyl sulphate showed a common periodic acid-Schiff positive band with an apparent molecular weight of about 64 000, when examined by polyacrylamide gel electrophoresis. A computer-assisted method for making linear radiographic measurements using stored regions of interest.

filibuvir pfizer patient

Studies of any qualitative design that examined the views and experiences of, and attitudes towards, HCV testing and diagnosis among PWID or practitioners involved in their care were included. Estimates of the relative volumes of the granules from these 3 groups were combined with previous results. For the first time in Korea, the diagnostic accuracy of test kits was evaluated by meta-analysis using STARD checklist. Photodissociation and recombination of carbonmonoxy cytochrome oxidase: dynamics from picoseconds to kiloseconds. I propose that alterations in the secretory activity of pineal melatonin during manic and depressive episodes may explain better both the higher risk of TD in patients with affective disorders and the mood-dependent fluctuations in severity of TD.

filibuvir pfizer careers

Next-generation sequencing identifies rare variants associated with Noonan syndrome. The levels of CMR factors were significantly higher in males than in females. Purdy pioneered structure-activity relationship studies on these compounds and developed innovative detection assays that are essential to assess their function in biological tissues. With an emphasis on the different morphologies of TiO2 and the influence factors in the synthesis, this review summarizes fourteen TiO2 preparation methods, such as the sol-gel method, solvothermal method, and reverse micelle method.

filibuvir pfizer animal health

BASIC requirements of a department of clinical pathology of a modern hospital. These results could provide a promising approach to treat breast cancer patients.

filibuvir hcv infection

How people try to end their lives has been linked to the risk of eventual suicide. Behavior of the activity of various glycolytic enzymes and aminopherases in the blood and tissues of animals treated with 6-aminonicotinamide Effect of mobilization of the posterior cardial wall on the completeness of selective proximal vagotomy Challenges in using high-fidelity simulation to improve learning and patient safety.

filibuvir pfizer patient

Tumour proliferative potentials may provide additional information on the behaviour of the tumour, its response to treatment and prognosis. Progesterone, chlormadinone and medroxyprogeste rone induced the fine structural changes characteristic of postovulatory human endometrium when added to cultures of proliferative human endometrium. One hundred twenty-eight renal allograft recipients were randomly assigned (1:1) to receive reduced-dose tacrolimus plus sirolimus (rTAC) or standard-dose tacrolimus and sirolimus (sTAC) for 6 months.

filibuvir pfizer inc

There was a significant influence of the botanical and geographical provenance as well as technological processing on the elemental composition of honeys. The assessment of efficacy was based on the absence of repeated II within 5 years of therapy. The effect of nicotinic acid on the depressant action of ethanol and pentobarbital. Coagulation system (1) PIVKA II: In all cases, PIVKA II was negative.

filibuvir side effects

Injured respiratory mucosa repaired rapidly, whereas olfactory mucosa continued to exfoliate at 44 hours after exposure. Water bottles used for rinsing tracheal suction connecting tubing were found to contain P paucimobilis organisms.

filibuvir synthesis protein

Postoperatively, a significant reduction of ventricular extrasystole was evident. Insight test prognosis in successful and unsuccessful rehabilitation of the blind. Study of the role of arginine residues in bacterial formate dehydrogenase.

filibuvir pfizer

Evidence for a mechanism for the initiation of acid hydrolase secretion by macrophages that is functionally independent of alternative pathway complement activation. Amino-aciduria with cystinosis: case report with determination of urinary amino acids and ocular cystine. This imbalance theory has been frequently used to legitimize the potential for increased cardiovascular risk associated with the use of these agents. The trained midwives, on the other hand, know modern obstetrical techniques but are not familiar with the lifestyles of their patients. On the modification of the virulence of tumors by chemotherapeutic agents.

filibuvir pfizer stock

Amino acids of the recombinant kringle 1 domain of human plasminogen that stabilize its interaction with omega-amino acids. In case of splenic masses, excision and spleen-conserving surgery or total splenectomy should be performed. A homologous biological probe for parathyroid hormone in human serum. Inferior vena cava filters are increasingly utilized to prevent pulmonary emboli originating from lower extremity, pelvis, or caval thromboses. In comparison with the method of using only human fibrin tissue adhesive to close recurrent perforations, this method has the advantage that even bigger perforations of the tympanic membrane can be closed.

inosine monophosphate dehydrogenase inhibitor ribavirin cost

  • ribavirin mechanism of resistance to infection
  • ribavirin dose timeshares
  • ribavirin iv dose
  • filibuvir mechanism of action
  • ribapak vs ribavirin virazole
  • lassa fever treatment ribavirin and interferon
  • ribavirin dosage in lassa fever
  • ribavirin drug manufacturer teva
  • filibuvir pfizer stock
  • ribavirin tablets usp monograph for water
  • filibuvir synthesis protein
  • ribavirin dosing schedule
  • peg interferon alfa-2a and ribavirin dose
  • filibuvir side effects
  • filibuvir pfizer allergan
  • filibuvir pfizer pharmaceuticals
  • filibuvir pfizer inc
  • filibuvir hcv symptoms
  • ribavirin treatment and side effects
  • hantavirus treatment ribavirin dosage
  • hplc ribavirin cost
  • filibuvir pfizer
  • ribavirin dosage form
  • pegylated interferon alfa 2a ribavirin treatment
  • parainfluenza treatment ribavirin dose
  • filibuvir hcv treatment
  • filibuvir pfizer careers
  • ribavirin dosage forms definition
  • filibuvir hcv infection
  • interferon ribavirin dosage dose
  • ribavirin administration safety shoes
  • faldaprevir deleobuvir and ribavirin treatment
  • filibuvir pfizer products
  • ribavirin nebulizer side effects
  • ribavirin weight based dosage calculations
  • hcv ribavirin dose rsv
  • peg interferon alfa-2a and ribavirin dosage
  • ribavirin cost generic for restasis
  • ribavirin 400 mg preiser's disease
  • ribavirin drug label for advil
  • filibuvir pfizer patient
  • igrice ribavirin side effects
  • ribavirin buccal tablets definition
  • treatment of ribavirin rash
  • ribavirin suspension
  • interferon ribavirin telaprevir manufacturer
  • inosine monophosphate dehydrogenase inhibitor ribavirin cost
  • ribavirin dose calculator mg/m2
  • ribavirin package insert inhalation
  • pegylated interferon plus ribavirin package
  • iv ribavirin dosage
  • filibuvir pfizer news
  • filibuvir pfizer logo
  • filibuvir pfizer viagra
  • filibuvir pfizer jobs
  • copegus ribavirin tablets medication
  • sovaldi and ribavirin reviews for
  • ribavirin recommended dosage
  • ribavirin drug monographs
  • ribavirin dose adjustment for warfarin
  • interferon ribavirin telaprevir drug
  • ribavirin administration safety solutions
  • peginterferon alfa and ribavirin cost
  • filibuvir pfizer connection
  • ribavirin rsv bronchiolitis symptoms
  • ribavirin and viagra side effects
  • ribavirin side effects vision benefits
  • pfizer filibuvir
  • filibuvir pfizer animal health
  • ribavirin dose reduction svrc
  • ribapak vs ribavirin prescribing
  • ribavirin dose reduction in triple therapy for helicobacter
  • ribavirin side effects rsv
  • fda press release sofosbuvir and ribavirin

filibuvir pfizer pharmaceuticals

Correlation with early coronary and left ventricular angiography. The acetylcholine (ACh)- and nitroglycerin (NTG)-induced hypotensive responses and aortic relaxations were significantly blunted in WT mice fed with an HS diet compared with an NS diet. The image analysis method not only enabled assessment of a large number of glomeruli, but also clearly demonstrated that glomerular injury was more severe in the juxtamedullary region than in the superficial cortex region. To investigate the activity of the T-type calcium channel (TCC) and the expression of its subtypes in overactive detrusor (OD) myocytes in rats after partial bladder outflow obstruction (PBOO). By contrast, spontaneous activity of the beta-globin promoter occurs only within a narrow range of injected DNA (0.2-1 ng).

filibuvir pfizer news

Synthetic pyrethroids caused slight tremours in the whole body accompanied by salivation. This study sought to evaluate the effect of macitentan on hospitalization of patients with symptomatic pulmonary arterial hypertension (PAH).

ribavirin dosage in lassa fever

Cleavage of the oxabridged seven-member ring, reductive dechlorination in the chloropyridinyl and cleavage of C-N between the chloropyridinylmethyl and imidazalidine ring are the main transformation pathways of CYC. Our aim was to assess endothelial function in physically healthy patients with schizophrenia and related psychoses and to compare the results with healthy controls. Both SHIPs and the state health assessments on which they are based are prerequisites for Public Health Accreditation Board national accreditation.

inosine monophosphate dehydrogenase inhibitor ribavirin cost

Cross-linked peptides derived from this protein were identified at high confidence and those species were in agreement with the crystal structure of BCA. Three groups, comprising a total of 27 experiments, were conducted using 9 dogs chronically instrumented for measurement of aortic and left ventricular pressure, left ventricular dP/dt, subendocardial segment length, diastolic coronary blood flow velocity, and cardiac output. As such, it presents a unique contribution to our knowledge of the history of learning disability nursing in the UK.

ribavirin iv dose

Highlighting two case reports, this article features a GBR technique that uses bone pins in combination with L-PRF membranes to provide both horizontal and vertical ridge augmentation at severely compromised implant sites. Retrospective analysis (Canadian Task Force classification II-2). The purpose of this study was to distinguish the characteristics of the CNV and the PINV in a group of children with reading disabilities or dyslexia and to compare them from a group of normal readers.

ribavirin drug monographs

This study highlights the gap in ongoing support for people postparticipation in cardiac rehabilitation programmes and the need for different levels of support during their recovery. Curcumin is a polyphenolic compound isolated from the rhizomes of the plant Curcuma longa and shows intrinsic anti-cancer properties.

peginterferon alfa and ribavirin cost

An Okinawan-based Nordic diet improves anthropometry, metabolic control, and health-related quality of life in Scandinavian patients with type 2 diabetes: a pilot trial. Although thrombomodulin restoration has received considerable attention, no reports have been published on the in vivo expression status of thrombomodulin.

parainfluenza treatment ribavirin dose

The composition of immune complexes (IC) found in 28 patients with HBsAg positive and negative acute and chronic hepatitis was analysed. Indications for prenatal diagnosis were advanced maternal age and fetal anomalies. However, the use of high-throughput drug screens to discover novel small-molecule inhibitors for CSC has been hampered by their instability in long-term cell culture. At the higher dose U-46619 also elicits a delayed tachypnea that remains delayed even if ABP is normal. The aim of this study was to review the results of off-pump (OPCAB) versus conventional on-pump coronary artery bypass surgery (CCAB) in high-risk patients.

ribavirin dose reduction in triple therapy for helicobacter

The study was powered to detect only very large effects on MRI activity so smaller but clinically meaningful effects cannot be excluded. The phylogenetic comparison with the genomes of Caprini highlights the ancient presence of chamois in Europe relative to the fossil record, and the old age of the chamois clade mtC that was split from the clade mtW in the early Pleistocene. Extracellular histones exert part of their prothrombotic activity through the stimulation of blood cells.

ribavirin administration safety shoes

We treated four nonpregnant, severely Rh-sensitized female volunteers with intensive plasma exchange and either promethazine 150 mg or prednisone 60 mg per day in an attempt to remove circulating anti-Rho(D) and prevent further synthesis of the antibody. When 10 or more eggs were retrieved (20 cases), the pregnancy rate was 50 percent.

faldaprevir deleobuvir and ribavirin treatment

Many available systemic therapies, however, are unsuitable for chronic administration due to the risk of cumulative toxicity. The difference in hemoglobin affinity for oxygen in blood of the coronary sinus and in mixed venous blood was shown in dog experiments. Comparison of resting capillary flow dynamics in the finger and toe nailfolds.

ribavirin dose timeshares

Their relationship to private practice, compared curriculums, patients, and other recent changes of merit were evaluated, and the results of the survey are presented. Participants who subsequently experienced vasovagal symptoms had a lower ratio between low and high frequency components (LF/HF HRV) of heart rate variability (HRV) before blood donation, suggesting lower sympathetic nervous system activity. Detection of SLC37A4 gene mutations is of great significance for the diagnosis, subtyping and outcome prediction of GSD patients. While glucocorticoids and the liganded glucocorticoid receptor (GR) have a well-established role in the maintenance of differentiation and suppression of apoptosis in breast tissue, the involvement of unliganded GR in cellular processes is less clear.

igrice ribavirin side effects

We demonstrate for the first time that rat kidneys can be preconditioned to attenuate ischemic-reperfusion injury and adenosine infusion before ischemic insult protects renal function via A(1) adenosine receptor activation. Effects of the small molecule Kir channel modulator VU573 and its inactive analog VU342. On second harmonic generation and multiphoton-absorption induced luminescence from laser-reshaped silver nanoparticles embedded in glass.

ribavirin dose reduction svrc

Dockers with repeated infections do not have decreased S-IgA values. Consumers also can influence significantly the adoption of OHS practices by demanding the protection of workers who are producing he goods that are sold in the global market. Predictive strength was measured by survival-adapted R(2) and PTE. To induce accelerated growth and myopia, guinea pigs wore a -5 diopter (D) lens over one eye from 4 to 11 days of age. An examination of the startle response during upper limb stretch perturbations.

pfizer filibuvir

Dying midguts express the rpr, hid, ark, dronc, and crq cell death genes, suggesting that the core cell death machinery is involved in larval midgut cell death. A 1H-15N NMR study of human c-Ha-ras protein: biosynthetic incorporation of 15N-labeled amino acids. Replacement of Cys-47 with alanine or serine decreases the affinity for GSH and triggers a positive kinetic cooperativity with respect to the substrate.

filibuvir hcv treatment

Response to selection for sensitivity to ethanol hypothermia: genetic analyses. Serum total thyroxine (TT4) and free T4 (FT4) concentrations were elevated and serum TSH was undetectable as frequently observed also in euthyroid amiodarone-treated patients. The present study was undertaken to identify the prevalence and pattern of refractive errors among the school-entrant children at King Abdul Aziz Medical City (KAMC), Riyadh city - Kingdom of Saudi Arabia.

ribavirin dosage in lassa fever

The mechanical resistance of the screwless morse taper implant system is lower than that of the ISR implant systems that might result in more frequent clinical complications. Six ovine carpometacarpal joints were used in the present study. The aim of this prospective treatment study was to present long-term results after angular stable plate fixation of displaced proximal humeral fractures and to detect which specific patient- and fracture-related parameters affect the clinical outcome.

ribavirin dosage form

typhimurium by up-regulating antibacterial mechanisms shortly after infection. We evaluated the effects of arginase and iNOS inhibition on distal lung mechanics and oxidative stress pathway activation in a model of chronic pulmonary allergic inflammation in guinea pigs. The liver cells are targets during DENV infection, and alteration of liver functions contributes to severe disease. Progress on relationship between exercise improving insulin resistance and AMP-activated protein kinase

filibuvir pfizer stock

In this group many apoptotic cells and damaged organelles were seen. Whether meal-related symptoms such as postcibal epigastric fullness and discomfort are caused by hypotonic gastric expansion or gastric hypertension is unknown.

filibuvir pfizer patient

The reality of human experience and meaning is profoundly more complex than the scientific approach of fragmentation for purposes of dissection and diagnosis. In a subset of 5 cases of UC showing a differentiated component (UC-D), the expression of p53 protein was also investigated. In in vivo adoptive transfer studies, bone marrow from placebo-treated LLC-bearers stimulated tumor establishment and metastasis, while the bone marrow of IFN-gamma-plus TNF-alpha-treated tumor-bearers diminished LLC establishment and metastasis. Cardiac function in chronic bronchitis: effects of pacing and plasma expansion. Early diagnosis and surgical removal of the tooth fragments could prevent undesirable foreign-body reactions and scarring.

filibuvir pfizer pharmaceuticals

Expression was also evident in in situ bladder carcinoma (Tis), which tends to progress rapidly to invasive cancer. A diagnosis of chronic intestinal pseudo-obstruction was made based on histopathological changes in intestinal biopsies. Research on the anthelmintic properties of various derivatives of the cinnamic series. Fasting mediated increase in p-BAD(ser155) and p-AKT(ser473) in the prefrontal cortex of mice.

 Show Hide 
ribavirin drug monographs 2018-08-31

The in vitro changes in tissue morphology indicate an irreversible zovirax ointment price philippines iphone course even after irradiation with the lowest dose, 30 Gy single dose. This sixfold compression in a self-generated filament does not require any means for dispersion compensation and is highly efficient.

lassa fever treatment ribavirin and interferon 2010-04-06

Severe hypophosphatemia with reduced adenosine triphosphate production has been implicated, but little data are available regarding electrolyte abnormalities. In addition, it was confirmed that repeated administration of liposomal l-OHP did not induce a significant anti-PEG IgM response, indicating that l-OHP encapsulated in PEG-coated liposomes was efficient in abrogating the ABC phenomenon. Major active compounds from Siwu decoction analogous formulae, including ligustilide, butylidene phthalide, senkyunolide, ferulic acid, gallic acid, peoniflorin, jioglutin A, catalpol, transanethole, zingiberone, commiphoric acid, eugenol, isorhamnetin-3-O-neohesperidoside, wulingzhic acid, alpha-cyperone, cyperene, costunolide, costic quetiapin neuraxpharm 400 mg acid, tetrahydropalmatine, protopine, amygdalin, 24-methylene cycloartanol, oleic acid, linoleic acid, 3-p-coumaroylquinic acid, hydroxysafflor yellow A, coptisine, berberine, jatrorrhizine, baicalein, baicalin, wogonin were collected to build component-protein networks based on PharmMapper database. In the present study, we investigated the effects of this conditioning stimulation with or without muscular paralysis in behavioural tests in rats.

ribavirin weight based dosage calculations 2013-05-05

It has been assumed that the Class II (metallo) aldolases are evolutionary more antirobe liquid primitive than their Class I (Schiff-base) analogs since the latter had only been found in eukaryotes. An elution procedure for visualization of adult hemoglobins in human blood smears. Plasma zinc levels and urinary zinc excretion were measured by atomic absorption spectrophotometry.

lassa fever treatment ribavirin and interferon 2019-03-06

Morphological studies of porcine muscle showed that at 4 h post-mortem, gaps had formed between muscle fibers and that the sarcolemma membrane borders appeared blurred. This study was undertaken to assess the potential of this approach in restoring levator muscle function in pantoprazole ivpb dosage patients with mitochondrial disease and ptosis.

filibuvir hcv symptoms 2013-02-25

Up to now, prevention strategies in cleaning seem to be insufficient. At every clinical assessment visit, samples for 25-hydroxyvitamin D (25(OH)D) measurements and quality of life questionnaires were taken. Both necrosis and apoptosis were noted in tizanidine sirdalud mr 6 mg melatonin human NP as forms of cell death with increased apoptosis in degenerative NP, which was further confirmed by the TUNEL assay.

ribavirin package insert inhalation 2014-11-08

Twenty-three patients (11 males and 12 females) with different psychiatric disorders who were apparently free of any cardiovascular disorders and underwent ECT were enrolled in the study. Of these, one had 3.2 mm shortening of the mandible, one had 1.4 mm shortening of the mandible, and one had no change in mandibular length but repositioning of the incisors. Long-term clinical course of patients carrying the Q703K mutation in the NLRP3 gene: a case series. Linoleate-dependent co-oxygenation of benzo(a)pyrene and benzo(a)pyrene-7,8-dihydrodiol by augmentin 1000 mg muadilleri rat cytosolic lipoxygenase.

ribavirin iv dose 2011-03-03

Suppression of pancreatic cancer osyrol generika drugstore by sulfated non-anticoagulant low molecular weight heparin. Importance of basal glucagon in maintaining hepatic glucose production during a prolonged fast in conscious dogs. The classification into groups was confirmed by using antiserum inactivation.

ribavirin dose timeshares 2016-05-23

Population are divided into different membrane structures on average. In latent growth analyses, women in CBSM reported greater improvements in PSQI sleep quality scores than controls, although there were no significant differences between conditions on PSQI total scores. Polymerase chain reaction and restriction fragment length polymorphism methods were applied to detect polymorphisms in MMP-3 Promoter (-1,171 6A/5A) (rs 731236) and VDR-Apa (rs 35068180). However, no signs of strong inflammatory reactions were noticed. Despite much progress, serum biomarkers correlate with antibiotique infection urinaire norfloxacin disease severity and predict responses to treatment that are needed.

ribapak vs ribavirin virazole 2010-06-30

Cardiac catheterization showed a left ventricular out-flow gradient which was increased by isoproterenol infusion. Inactivation of cyclin-dependent kinases (Cdks) and/or allopurinol dosing guidelines for amoxil cyclins in mice has changed our view of cell cycle regulation. Medium-sized retinoblastomas frequently invade outside the globe.

pegylated interferon alfa 2a ribavirin treatment 2014-08-13

Biosynthesis of silver nanoparticles by Bacillus stratosphericus spores and the role of levox antibiotics for tooth dipicolinic acid in this process. Depression and anxiety in early pregnancy are associated with risk for subsequent preeclampsia, a risk further increased by bacterial vaginosis. Although valid prognostic criteria are still lacking, it appears that male patients may be best treated by more radical operation and should be observed more closely during follow-up.