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Dute (Dutasteride)

Dute is an aza-steroid that is inasteride in which the tert-butyl group is replaced by a 2,5-bis(trifluoromethyl)phenyl group. A synthetic 4-azasteroid, Dute is a selective inhibitor of both the type 1 and type 2 isoforms of steroid 5alpha-reductase, an intracellular enzyme that converts testosterone to 5alpha-dihydrotestosterone. Dute is used for the treatment of symptomatic benign prostatic hyperplasia in men with an enlarged prostate gland. It has a role as an EC [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor and an antihyperplasia drug. It is an aza-steroid, a member of (trifluoromethyl)benzenes and a delta-lactam. It derives from a hydride of a 5alpha-androstane.

Other names for this medication:
Dutasteride, Deetor, Duodart, Duprost, Dutagen, Dutas, Dutasterida, Dute, Veltride,

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Studies on the stability of sodium taurocholate in different media and in the course of sterilization Local sweating responses during recovery sleep after sleep deprivation in humans.

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High-titer (1:30,000) antiglucagon antibodies were detected in a 14-month-old patient with nesidioblastosis who had been treated by intramuscular long-acting glucagon since age 5 months. The detection and differential diagnosis of extruded (free) disk fragments by CT has not been described in detail. Since its introduction a few years ago, multidetector row CT (MDCT) has become a widely used diagnostic procedure and has been proven to be a valuable tool for various indications. Repetitive transcranial magnetic stimulation treatment showed benefits in the short term, but the long-term effects are questionable.

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A newly developed mouse monoclonal SOX10 antibody is a highly sensitive and specific marker for malignant melanoma, including spindle cell and desmoplastic melanomas. In most cases, the fastest mode observable for ternary mixtures is associated with the thermal diffusivity. During transplantation, cyclosporine was administered for prophylaxis against graft-versus-host disease, but she developed respiratory failure after she was weaned off the drug.

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The aim of this study was to provide data about hospital activity related to AHF at a national and regional level. DNA synthesis by CHO cell extracts on fork-like DNA templates containing the major cisplatin adduct requires a ligation step. Radical surgery in the management of clear cell adenocarcinoma of the cervix and vagina in young women. Hypophysectomized male rats, approximately 40 days of age, received GH at doses of 5, 25 and 62.5 micrograms/day administered in two injections/day at 08.00 and 16.00 h. The goal of this study was to determine the antimicrobial resistance patterns of blood isolates from pediatric oncology patients in Iran to determine if there was significant resistance to quinolones.

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Demand-controlled desynchronization of brain rhythms by means of nonlinear delayed feedback. Development of on-bed lower extremity exercise system for use with networked virtual space. We discuss situations in which this alternative, which we call DES C, is preferred.

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A high index of clinical suspicion is necessary for prompt diagnosis. Students performed a structured cardiovascular risk intervention on a patient in primary care clinics. To investigate the prevalence of ear diseases, other otological risk factors potentially affecting hearing, and noise exposure among adults. Extracerebral fluid collections in infancy: role of magnetic resonance imaging in differentiation between subdural effusion and subarachnoid space enlargement. The solubilization of steroid esters by 2-HP-beta-CD depended on the structure and length of the ester side chain.

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Electrically elicited cardiovascular and respiratory responses from the nucleus tractus solitarii in unrestrained cats. The recent introduction of clinically available next generation sequencing (NGS) cancer panels has presented new challenges for genetic counselors.

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The concentration of MGC was improved in the kidney except for other tissues, about 6.76 times higher than that of MPA. Accumulating evidence showed that transient receptor potential channels play an important role in the regulation of cardiomyocyte differentiation. Current status of meningococcal group B vaccine candidates: capsular or noncapsular?

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The National Kidney Foundation Council on Renal Nutrition addresses the Food and Drug Administration. Angiographic characteristics of coronary arterial segments progressing to myocardial infarction in patients with and without chronic kidney disease. The neuropeptide oxytocin was first noted for its capacity to promote uterine contractions and facilitate delivery in mammals.

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Especially when a low-dose curietherapy is applied without dose monitor, a radiation exposure of bladder and rectum exceeding the tolerance limit or a underdosage in the target volume are possible due to variable positions of the uterus and different thicknesses of the uterus wall, above all in the region of the cervix. Interleukin-1 modulates GABAergic and glutamatergic function in brain.

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The pathophysiological mechanisms underlying this condition are still incompletely understood. A 9-h lag in growth was observed, during which butyryl-CoA, a degradation product of ethylmalonyl-CoA, accumulated, suggesting a metabolic imbalance.

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Describing an Early Social Work Intervention Program for Families after Severe Traumatic Brain Injury. Therefore, changing IL-18 ratio may be an early predictor for AKI after OLT. Solutions to these challenges include students and their pharmacist supervisors to find ways to present their collaborative needs to physicians and for students to illustrate more explicitly the benefits patient achieve if physicians implement the recommendations of students. The plasma concentrations of creatine kinase (CK), lactate dehydrogenase (LDH), and creatinine rose early in infection and showed highly significant increases terminally. siRNA could block the endogenous VEGF-C genes and the protein expression in gastric cancer cell.

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Next, we examined the expression of ET-1 and ETR-A in hMSC using proliferation or calcification assay. The patient subsequently found a live parasite emerged from his lower eyelid and it was successfully removed by himself. The research data, in the aggregate, suggest that the presence of melancholia predicts a poor response to psychotherapy and placebo and a relatively good response to antidepressants and ECT. As for other extra-vertebral sites of vertebral hyperostosis, the foot warrants careful examination. To investigate whether breast feeding is related to family type, family size, maternal education, maternal occupational status and ethnic origin.

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Specific antibody response of normal persons subjected to repeated injections of Vi antigens Household modelling and forecasting--dynamic approaches with use of linked census data.

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Corticosteroids may be especially useful in pseudophakic patients poorly responsive to anti-VEGF therapies, in patients wishing to reduce the number of required injections, and in pregnant patients. This can be explained in terms of marriage protection and marriage selection. We applied a tumor stem cell assay using an enriched double-layered soft agar system for the detection of metastatic sites of lung cancer. A stepwise, simple screening test for skin and eye irritations, suitable for industrial chemicals or pesticides which are not required to be examined for their exact potential irritancy levels, was developed.

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Analysing consumption of specific dementia drugs can be a reliable and inexpensive means of updating prevalence data periodically and helping rationalise healthcare resources. The formation rate of 99mTc-Cu-EHDP complex with a high labelling yield was fast and achieved within a few mins.

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Experiments and calculations show localized plasmon resonance for the polarization orthogonal to the wire (far-field resonance at 580 nm for the smallest wire and 670 nm for the widest). Food hygiene as applied to the marketing and distribution of fish. Iliac angiograms performed by carotid artery approach determined the hemostasis time. Treatment of urological complications after radical Wertheim operations

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High-fat diet for 8 weeks, not 2 weeks, induced hepatic steatosis and increased hepatic triglyceride content, all of which were ameliorated by MR16-1 treatment. Steady and transient two-dimensional thin-jet flow of a viscoelastic is examined theoretically. At the end of the 4th and 20th weeks of postnatal life, the animals were sacrificed, and right optic nerves were excised and sectioned for ultrastructural and stereological analyses.

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The second specimen is dead eight hours after the bite, an anatomopathological study shows oedematous and haemorrhagico lesions of the conjunctive and striated muscular tissues. Within a 4-month period, she underwent a total of 6 PVP operations with 13 cement-augmented vertebral bodies from T5-L5. We analyze the interactions between two Kondo quantum dots connected to a Rashba-active quantum wire.

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Conformal intensity-modulated radiation therapy (IMRT) involves irradiation of large volume of normal tissue with low and medium doses, biological relevance of which is not clear yet. Initial design of culturally informed behavioral intervention technologies: developing an mHealth intervention for young sexual minority men with generalized anxiety disorder and major depression.

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To describe the trends in the proportion of pediatric trauma patients acutely hospitalized in trauma-designated versus non-trauma-designated hospitals. The rapid emergence of antibiotic resistance in pathogenic microbes is becoming an imminent global public health problem. In each thyroxine binding site there are three pairs of symmetry related halogen binding pockets which can accommodate the four iodine substituents of thyroxine.

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After stress, 20 microg of medetomidine/kg was administered IM on days 1, 3, and 8. Low-income parents of preschool-aged children described a diverse set of considerations and strategies related to portion sizes of snack foods offered to their children. Over the years many well-described techniques for the introduction of transgene DNA into host organisms have been used, including pronuclear injection, in vitro fertilization-mediated transgenesis, transfection of ES and spermatogenic cells, nuclear transfer of somatic cell nuclei, and lentiviral vectors.

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Samples were retrospectively collected from a series of 195 pathological stage I/II pancreatic cancer patients who underwent potentially curative surgery between June 2010 and April 2014. Determinants for membrane association and permeabilization of the coxsackievirus 2B protein and the identification of the Golgi complex as the target organelle. The muscle weakness responded to treatment with neostigmine and the microfilariae disappeared after treatment with levamisole. This revealed only the juxtaglomerular binding and successfully suppressed binding of the radioligand to other sites.

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Even though the Brazilian laws prohibit the fisheries of threatened species, L. We present dielectrophoresis (DEP) and electrorotation (ROT) measurements of gold-coated polystyrene microspheres as a function of frequency and for several electrolyte conductivities. We concluded that the current available evidence do not support an association between thimerosal and childhood neurodevelopmental disorders, such as autism. Subplasmalemmal linear densities, consisting of a thin layer of electron-dense material immediately subjacent to the inner leaflet of the plasma membrane, were found in 30 of the 33 patients, including each of 6 patients with pulmonary sarcoidosis, 18 of 19 patients with idiopathic pulmonary fibrosis, 4 of 5 patients with collagen-vascular diseases, 1 patient with pulmonary lymphangioleiomyomatosis, and 1 patient with marked interstitial pulmonary fibrosis associated with squamous cell carcinoma of the lung. To determine whether immune deviation is induced by allogeneic corneal tissue implanted in the anterior chamber and whether survival of subsequent orthotopic corneal allografts is thereby enhanced.

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PDZD7, a paralog of two USH causative genes, USH1C and USH2D (WHRN), was recently reported to be implicated in USH2 and non-syndromic deafness. A patient who has azoospermia on 2 consecutive semen analyses at an interval of 5-6 weeks is considered infertile.

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Alkaline phosphatase has been studied in hydrophobic interaction chromatography (HIC), using a bonded C1-ether phase on a silica gel support, together with an aqueous salt gradient. Comparative proteome analysis of N-89 sensitive and NRC10 strains revealed over-expression of 12 spots and down-regulation of 14 spots in NRC10. Gel-shift analysis using restriction fragments spanning the sequence between position -237 and -143 revealed two distinct nuclear protein-DNA interactions.

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Tick salivary molecules injected into the host modulate host defence responses to the benefit of the feeding ticks. Porosity makes powerful affinity materials for quartz crystal microbalances. Characterization of reaction centers from photosynthetic bacteria.

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Lower numbers of bacteria were observed in the liver and spleen in response to IL-1 pretreatment shortly after infection in all Ityr strains of mice tested, including the congenic C.D2-Ityr mice. Some comparisons are also made with the morphology of the human mesentery. Outer membranes were isolated from Haemophilus parainfluenzae HP-28 by a mild extraction method followed by Sephadex G-150 gel filtration chromatography. Factors contributing to protection against experimental tuberculosis have been studied with refined and well-characterized fractions from mycobacteria and with certain unrelated antigens. This report describes the clinical and histologic features of this extremely rare case of sarcomatoid SDC with reference to the relevant literature.

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Poster 50 Torsional Anatomy of the Lower Limb: The Appearance of Anatomy in Hemispastic Position. Subjects who had first watched the violent videotape showed no differences in aggression as a function of the justification of the second set of aggressive acts. The present study indicates that this inverse relationship is caused by a dose-related induction of kidney damage leading to increasing leakage of mercury through the kidneys.

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Young Friesian horses show familial aggregation in fitness response to a 7-week performance test. Influence of superior cervical ganglion stimulation of vestibular function Using this ROI, combined with an abdominal skinfold measurement, we have derived an equation to predict IAAT in overweight/obese postmenopausal women.

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The plasmid RP4::Mu cts62 in stably inherited by Erwinia carotovora 268 strain. In order to support the widely diversified parenchymal cells and tissue organization, MSCs are characterized by a large degree of heterogeneity, although available analyses of molecular and transcriptional data do not provide clear evidence. Towards a better understanding of readmissions after stroke: partnering with stroke survivors and caregivers. Priming effects increase nonlinearly as a function of both the number and the position of shared letters, and they are dependent on the positions of letters relative to both the end positions in the string and to the identities of their nearest neighbours. Multiple antibody formation in a primigravida: anti-D, anti-C, anti-Kpb.

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Tumor induction by human adenovirus type 12 in hamsters: loss of the viral genome from adenovirus type 12-induced tumor cells is compatible with tumor formation. Review of in vivo studies of dimethyl sulfoxide cryopreserved platelets.

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Non-invasive assessment of adrenocortical function in captive Nile crocodiles (Crocodylus niloticus). Committees will be set up in the selected villages in Capiz in order to establish detailed plans and implementation. Trophic transfer of toxic elements in the estuarine invertebrate and fish food web of Daliao River, Liaodong Bay, China. A neuropsychiatric reconditioning program in the peacetime Army. Alcohol misuse is a common cause of liver disease, upper gastrointestinal (GI) bleeding, and pancreatitis, but it is not known whether alcohol screening questionnaires can identify patients at increased risk for hospitalizations due to these conditions.

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All 12 eyes developed acute optic neuritis (with variable degrees of optic disc edema and visual loss). The thresholds of discriminating the duration of frequency-modulated signals by cats behaving freely In this chapter, methodologies for the extraction and HPLC analysis of these compounds are described as well as a widely used protocol to assess sitavig reviews their antioxidant capacity. Pulse oximetry plus clinical assessment is feasible and reliable for the detection of major congenital heart disease in newborn babies in China. The objective of this study was to examine the prevalence of negative symptoms in the presence of significant levels of depression and in the absence of such symptoms (primary negative symptoms) over 1 year and to examine differences in negative symptoms in psychosis converters and non-converters.

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Magnetic resonance imaging (MRI) of the brain was performed on a group of 24 recently detoxified, male alcoholics approximately 1 month after their date of last drink. This study illustrates the potential of using PBTK/TD modelling in the safety assessment relaxol paracetamol during pregnancy of nicotine-containing products. No molecular events underlying the reduction of FLNA levels in resistant tumors have been so far identified.

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Lung mast cell hyperplasia and histaloc dosage pulmonary histamine-forming capacity in hypoxic rats. As society has become increasingly inquisitive about complementary therapies, various sectors of the medical community have begun to incorporate complementary therapies into their practice, studying their impact on client health and effectiveness in treating specific symptoms.

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A four week sino-aortic denervation produces an increase of adrenaline (A) turnover in the anterior but not the posterior hypothalamus and a selective reduction of dopamine stores in the anterior hypothalamus. Five-year outcomes of chronic total occlusion treatment with a biolimus A9-eluting biodegradable polymer stent versus a sirolimus-eluting permanent polymer stent in the LEADERS all-comers binoclar antibiotic trial. Guppy (Lebistes reticulatus) embryos pass through a distinct sequence of motor behaviors that leads to swimming capability during the course of their development.

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